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. 2013 Aug;2(3-4):365-6.
doi: 10.1159/000343851.

Molecular Link between Liver Fibrosis and Hepatocellular Carcinoma

Toshiharu Sakurai  1 , Masatoshi Kudo  1
Affiliations

Molecular Link between Liver Fibrosis and Hepatocellular Carcinoma

Toshiharu Sakurai et al. Liver Cancer. 2013 Aug.
No abstract available

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References

    1. Thorgeirsson SS, Grisham JW. Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet. 2002;31:339–346. [Medline] - PubMed
    1. Ghany MG, Kleiner DE, Alter H, Doo E, Khokar F, Promrat K, Herion D, Park Y, Liang TJ, Hoofnagle JH. Progression of fibrosis in chronic hepatitis C. Gastroenterology. 2003;124:97–104. [Medline] - PubMed
    1. Sakurai T, Kudo M, Umemura A, He G, Elsharkawy AM, Seki E, Karin M. p38α Inhibits Liver Fibrogenesis and Consequent Hepatocarcinogenesis by Curtailing Accumulation of Reactive Oxygen Species. Cancer Res. 2013;73:215–224. [Medline] - PMC - PubMed
    1. Ramakrishna G, Rastogi A, Trehanpati N, Sen B, Khosla R, Sarin SK. Cirrhosis to hepatocellular carcinoma: Newer molecular insights on inflammation and cellular senescence. Liver Cancer 2013 (in press). - PMC - PubMed
    1. Sakurai T, He G, Matsuzawa A, Yu GY, Maeda S, Hardiman G, Karin M. Hepatocyte necrosis induced by oxidative stress and IL-1α release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis. Cancer Cell. 2008;14:156–165. [Medline] - PMC - PubMed