Prevalence and Management of Dyslipidemia in Korea: Korea National Health and Nutrition Examination Survey during 1998 to 2010

Abstract

Background: Dyslipidemia is a major risk factor of cardiovascular disease. The aim of this study was to investigate the changing trends in the prevalence and management status of dyslipidemia among Korean adults.

Methods: The prevalence of dyslipidemia and the rates of awareness, treatment, and control of dyslipidemia were investigated in adults aged ≥20 years from the Korea National Health and Nutrition Surveys (KNHANES) 1998 to 2010. The updated National Cholesterol Education Program criteria was used, which define dyslipidemia as having one or more of the following lipid abnormalities: hypercholesterolemia (total cholesterol ≥240 mg/dL or diagnosis of dyslipidemia or use of lipid-lowering drugs), hypertriglyceridemia (≥150 mg/dL), hyper-low density lipoprotein (LDL) cholesterolemia (≥160 mg/dL or diagnosis of dyslipidemia or use of lipid-lowering drugs), and hypo-high density lipoprotein (HDL)-cholesterolemia (<40 mg/dL in men and <50 mg/dL in women).

Results: The number of participants was 6,921, 4,894, 5,312, 2,733, 6,295, 6,900, and 5,738 in KNHANES 1998, 2001, 2005, 2007, 2008, 2009, and 2010, respectively. Age-standardized prevalence rates of dyslipidemia were 54.0%, 65.8%, 66.5%, 60.6%, 58.7%, 58.9%, and 59.0% in 1998, 2001, 2005, 2007, 2008, 2009, and 2010, respectively. Hypertriglyceridemia and hypo-HDL-cholesterolemia were the two most frequent lipid abnormalities. The overall prevalence of hypercholesterolemia and hyper-LDL-cholesterolemia increased by 1.36- and 1.35-fold in 2010 compared with 2007, respectively. Awareness, treatment, and control rates of dyslipidemia improved over the period of surveys in both sexes. In 2010, about 30% of dyslipidemic patients who received lipid-lowering treatment reached target levels.

Conclusion: Although the management status of dyslipidemia has improved during recent years, effective strategy is required for achieving better prevention, treatment, and control of dyslipidemia.

Keywords: Dyslipidemia, Korea; Prevalence.

Fig. 1

Prevalence rates of dyslipidemia and each factors of it according to sex in the Korea National Health and Nutrition Survey during 2007 to 2010. (A) Men. (B) Women. Hyper-chol, hypercholesterolemia; Hyper-LDL, hyper-low density lipoprotein-cholesterolemia; Hyper-TG, hypertriglyceridemia; Hypo-HDL, hypo-high density lipoprotein-cholesterolemia.

Fig. 2

Prevalence rates of dyslipidemia and its individual lipid abnormalities by sex and age-category in the 2010 Korea National Health and Nutrition Survey. LDL, low density lipoprotein; HDL, high density lipoprotein.

Fig. 3

Prevalence rates of dyslipidemia and its individual components according to the presence of diabetes in the Korea National Health and Nutrition Survey during 1998 to 2010. LDL, low density lipoprotein; HDL, high density lipoprotein.