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Review
. 2013 Dec;5(12):671-9.
doi: 10.4103/1947-2714.123239.

Clinicopathological prognostic implicators of oral squamous cell carcinoma: need to understand and revise

Kiran B Jadhav  1 , Nidhi Gupta  1
Affiliations
Review

Clinicopathological prognostic implicators of oral squamous cell carcinoma: need to understand and revise

Kiran B Jadhav et al. N Am J Med Sci. 2013 Dec.

Abstract

In spite of the vast amount of research and the advances, oral squamous cell carcinoma implies quite significant mortality and morbidity rates. This has motivated the search of factors with prognostic relevance. A web based search was initiated for all published articles by using Medline/PubMed, Google Scholar with key words such as prognosis, survival rate, risk factors associated with oral squamous cell carcinoma, prognosis of oral squamous cell carcinoma. The search was restricted to articles published in English language with no restriction to date of publication. This review was focused on clinical, pathological and molecular factors associated with survival and prognosis of oral squamous cell carcinoma patients. Most articles had described one or two parameters related to prognosis. Considering the biological behavior and nature of cancer, all the parameters were interrelated and so could not predict the prognosis independently. Consideration of all the parameters was required to assess the prognosis. We hypothesize the use of combination of clinical and pathological indicators together to assess the prognosis. The care givers can assess the prognosis in a more better and definitive way by using prognosis assessment sheet.

Keywords: Oncogenes; oncoviruses; oral squamous cell carcinoma; prognosis in oral cancer; tumer node metastasis staging.

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Conflict of interest statement

Conflict of Interest: None declared.

References

    1. Novak KF, Goodman SF, Takei H. Determination of prognosis. In: Newman M, Takei H, Klokkevold P, Carranza F, editors. Carranza's’ Clinical Periodontology. 10th ed. New Delhi: Elsevier Publisher; 2007. p. 614.
    1. Daugherty CK, Hlubocky FJ. What are terminally ill cancer patients told about their expected deaths? A study of cancer physician's self-reports of prognosis disclosure. J Clin Oncol. 2008;26:5988–993. - PMC - PubMed
    1. New York: Oral Cancer Incidence (New Cases) by Age, Race and Gender, Inc; c2004. [updated 25 March 2011; accessed on 8 June 2013]. Cancer incidence.org (Internet) at http://www.nidcr.nih.gov/datastastics/finddatabytopic/oralcancer/oralcan... .
    1. Rosebush M, Samant S, Handorf C, Nosrat C. Oral cancer: Enduring characteristics and emerging trends. J Tenn Dent Assoc. 2011;91:24–7. - PubMed
    1. Camisasca DR, Silami MA, Honorato J, Dias FL, de Faria PA, Lourenço Sde Q. Oral squamous cell carcinoma clinicopathological features in patients with and without recurrence. ORL J Otorhinolaryngol Relat Spec. 2011;73:170–6. - PubMed