On the primacy of primordial RNA
- PMID: 2440500
- DOI: 10.1016/0303-2647(87)90043-8
On the primacy of primordial RNA
Abstract
The ability of RNA to catalyze biochemical reactions is used to develop a self-consistent picture of how a primordial RNA could have given rise to the necessary factors and processes of early life forms. Essential to this proposal is the impact of RNA structural domains, "selected" by thermodynamic criteria, on the structure of early proteins (exons) and the assembly of functional complexes. Based on this analysis, the chronological appearance of informational molecules follows the order: primordial RNA, proteins whose structures are determined by primordial RNA sequences and finally DNA.
Similar articles
-
From records to self-description: the role played by RNA in early evolutive systems.Acta Biotheor. 1992 Mar;40(1):1-9. doi: 10.1007/BF00046546. Acta Biotheor. 1992. PMID: 1378239 Review.
-
Proteins, exons and molecular evolution.Biosystems. 1987;20(2):181-206. doi: 10.1016/0303-2647(87)90044-x. Biosystems. 1987. PMID: 3038209
-
The evolutionary transition from RNA to DNA in early cells.J Mol Evol. 1988;27(4):283-90. doi: 10.1007/BF02101189. J Mol Evol. 1988. PMID: 2464698
-
Molecular evolution of transfer RNA from two precursor hairpins: implications for the origin of protein synthesis.J Mol Evol. 1995 Jul;41(1):1-9. doi: 10.1007/BF00174035. J Mol Evol. 1995. PMID: 7608982
-
Exploratory studies to investigate a linked prebiotic origin of RNA and coded peptides.Chem Biodivers. 2004 Feb;1(2):203-46. doi: 10.1002/cbdv.200490020. Chem Biodivers. 2004. PMID: 17191842 Review.
Cited by
-
From records to self-description: the role played by RNA in early evolutive systems.Acta Biotheor. 1992 Mar;40(1):1-9. doi: 10.1007/BF00046546. Acta Biotheor. 1992. PMID: 1378239 Review.
-
An RNA replisome as the ancestor of the ribosome.J Mol Evol. 1991 Jan;32(1):3-5. doi: 10.1007/BF02099922. J Mol Evol. 1991. PMID: 1707098 Review.
-
The relationship between RNA catalytic processes.Orig Life Evol Biosph. 1988;18(3):299-305. doi: 10.1007/BF01804676. Orig Life Evol Biosph. 1988. PMID: 2465524
-
The RNA-world and co-evolution hypotheses and the origin of life: implications, research strategies and perspectives.Orig Life Evol Biosph. 1993 Dec;23(5-6):329-44. doi: 10.1007/BF01582084. Orig Life Evol Biosph. 1993. PMID: 7509476 Review.
-
The origin and amplification of biomolecular chirality.Orig Life Evol Biosph. 1991;21(2):59-111. doi: 10.1007/BF01809580. Orig Life Evol Biosph. 1991. PMID: 1758688 Review. No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources