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Comment
. 2014 Jan 6;24(1):R31-R33.
doi: 10.1016/j.cub.2013.11.022.

Actin dynamics: cell migration takes a new turn with arpin

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Actin dynamics: cell migration takes a new turn with arpin

Douwe Veltman. Curr Biol. .
Free article

Abstract

Accurate cell migration requires intricate control over the actin cytoskeleton. Recent work has identified an Arp2/3-interacting protein called Arpin, which restricts the rate of actin polymerization and is the latest component in the steadily expanding protein repertoire that controls cell migration.

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  • Inhibitory signalling to the Arp2/3 complex steers cell migration.
    Dang I, Gorelik R, Sousa-Blin C, Derivery E, Guérin C, Linkner J, Nemethova M, Dumortier JG, Giger FA, Chipysheva TA, Ermilova VD, Vacher S, Campanacci V, Herrada I, Planson AG, Fetics S, Henriot V, David V, Oguievetskaia K, Lakisic G, Pierre F, Steffen A, Boyreau A, Peyriéras N, Rottner K, Zinn-Justin S, Cherfils J, Bièche I, Alexandrova AY, David NB, Small JV, Faix J, Blanchoin L, Gautreau A. Dang I, et al. Nature. 2013 Nov 14;503(7475):281-4. doi: 10.1038/nature12611. Epub 2013 Oct 16. Nature. 2013. PMID: 24132237

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