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Comment
. 2014 Jan 9;123(2):154-6.
doi: 10.1182/blood-2013-11-538256.

A straight neutrophil path to healthy aging?

Paul H Naccache  1 , Julie S Lefebvre
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A straight neutrophil path to healthy aging?

Paul H Naccache et al. Blood. .
Free article

Abstract

In this issue of Blood, Sapey et al. report that the human polymorphonuclear neutrophil leukocyte (or neutrophil) undergoes an age-related loss of its ability to migrate up chemotactic gradients, a functional defect that seems causally related to alterations in the polyphosphoinositide pathway.

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