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Observational Study
. 2014 Aug;29(5):452-6.
doi: 10.1177/1533317513518654. Epub 2014 Jan 8.

Gastritis May Boost Odds of Dementia

Yadollah Abolfathi Momtaz  1 , Tengku Aizan Hamid  2 , Rahimah Ibrahim  3
Affiliations
Observational Study

Gastritis May Boost Odds of Dementia

Yadollah Abolfathi Momtaz et al. Am J Alzheimers Dis Other Demen. 2014 Aug.

Abstract

Introduction: Given the high prevalence of dementia and its devastating consequences, identifying risk factors for dementia is a public health priority. The present study aims to assess whether gastritis increases the odds of dementia.

Methodology: The data for this study, consisting of 2926 community-dwelling older adults, were obtained from the National survey entitled "Mental Health and Quality of Life of Older Malaysians." Dementia was diagnosed using the Geriatric Mental State-Automated Geriatric Examination for Computer-Assisted Taxonomy.

Results: Prevalence of dementia was considerably higher among older adults with gastritis (29.5%) compared to those without gastritis (13.2%). After adjusting for age, gender, marital status, educational attainment, hypertension, stroke, and diabetes, gastritis was significantly associated with more than twice odds of dementia (adjusted odds ratio = 2.42, P < .001, 95% confidence interval = 1.68-3.49).

Conclusions: The findings from this population-based observational study showing evidence that gastritis may increase the risk of dementia provide avenue for further inquiries into dementia.

Keywords: aged; dementia; gastritis; risk factor.

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Conflict of interest statement

The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Underlying mechanism by which gastritis may increase risk of dementia.
See this image and copyright information in PMC

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