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. 2014 Feb 3;55(2):650-3.
doi: 10.1167/iovs.13-13330.

Ocular surface symptoms in veterans returning from operation Iraqi freedom and operation enduring freedom

Yasha S Modi  1 , Qirat Qurban, Leonid Zlotcavitch, Roberto J Echeverri, William Feuer, Hermes Florez, Anat Galor
Affiliations

Ocular surface symptoms in veterans returning from operation Iraqi freedom and operation enduring freedom

Yasha S Modi et al. Invest Ophthalmol Vis Sci. .

Abstract

Purpose: To correlate situational exposures and psychiatric disease with self-reported ocular surface symptoms in a younger veteran population involved in Operation Iraqi Freedom and Operation Enduring Freedom (OIF/OEF).

Methods: Cross-sectional study of all veterans evaluated in the OIF/OEF clinic between December 2012 and April 2013 who completed the dry eye questionnaire and screening evaluations for environmental exposures, posttraumatic stress disorder (PTSD), and depression. The main outcome measures were the influence of environmental exposure and psychiatric disease on ocular surface symptoms.

Results: Of 115 participants, the average age was 33 years. While overseas, exposure to incinerated waste (odds ratio [OR] 2.67, 95% confidence interval [CI] 1.23-5.81, P = 0.02) and PTSD (OR 2.68, 95% CI 1.23-5.85, P = 0.02) were associated with self-reported ocular surface symptoms. On return to the United States, older age (OR per decade 2.66, 95% CI 1.65-4.31, P = 0.04) was associated with persistent symptoms and incinerated waste was associated with resolution of symptoms (OR 0.25, 95% CI 0.07-0.90, P = 0.04). When evaluating symptom severity, 26% of the responders complained of severe ocular surface symptoms, with PTSD (OR 3.10, 95% CI 1.22-7.88, P = 0.02) and depression (OR 4.28, 95% CI 1.71-10.68, P = 0.002) being significant risk factors for their presence.

Conclusions: PTSD was significantly associated with ocular surface symptoms both abroad and on return to the United States, whereas air pollution in the form of incinerated waste, was correlated with reversible symptoms.

Keywords: PTSD; depression; dry eye symptoms; environmental exposure; posttraumatic stress disorder.

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References

    1. Schaumberg DA, Sullivan DA, Buring JE, Dana MR. Prevalence of dry eye syndrome among US women. Am J Ophthalmol. 2003; 136: 318–326 - PubMed
    1. Schaumberg DA, Dana R, Buring JE, Sullivan DA. Prevalence of dry eye disease among US men: estimates from the Physicians' Health Studies. Arch Ophthalmol. 2009; 127: 763–768 - PMC - PubMed
    1. Yu J, Asche CV, Fairchild CJ. The economic burden of dry eye disease in the United States: a decision tree analysis. Cornea. 2011; 30: 379–387 - PubMed
    1. Lemp MA. Epidemiology and classification of dry eye. Adv Exp Med Biol. 1998; 438: 791–803 - PubMed
    1. The epidemiology of dry eye disease: report of the Epidemiology Subcommittee of the International Dry Eye WorkShop. Ocul Surf. 2007; 5: 93–107 - PubMed

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