Synaptic plasticity and the Warburg effect
- PMID: 24411936
- DOI: 10.1016/j.cmet.2013.12.012
Synaptic plasticity and the Warburg effect
Abstract
Functional brain imaging studies show that in certain brain regions glucose utilization exceeds oxygen consumption, indicating the predominance of aerobic glycolysis. In this issue, Goyal et al. (2014) report that this metabolic profile is associated with an enrichment in the expression of genes involved in synaptic plasticity and remodeling processes.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
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Aerobic glycolysis in the human brain is associated with development and neotenous gene expression.Cell Metab. 2014 Jan 7;19(1):49-57. doi: 10.1016/j.cmet.2013.11.020. Cell Metab. 2014. PMID: 24411938 Free PMC article.
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