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. 1987 Aug;328(6131):596-600.
doi: 10.1038/328596a0.

A small catalytic oligoribonucleotide

O C Uhlenbeck

A small catalytic oligoribonucleotide

O C Uhlenbeck. Nature. 1987 Aug.

Abstract

A 19-nucleotide RNA fragment can cause rapid, highly specific cleavage of a 24-nucleotide RNA fragment under physiological conditions. Because each 19-mer can participate in many cleavage reactions, this molecule has all the properties associated with an RNA enzyme.

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