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. 1987 Aug;328(6132):686-91.
doi: 10.1038/328686a0.

The Drosophila clock gene per affects intercellular junctional communication

T A Bargiello, L Saez, M K Baylies, G Gasic, M W Young, D C Spray

The Drosophila clock gene per affects intercellular junctional communication

T A Bargiello et al. Nature. 1987 Aug.

Retraction in

  • Per--no link to gap junctions.
    Saez L, Young MW, Baylies MK, Gasic G, Bargiello TA, Spray DC. Saez L, et al. Nature. 1992 Dec 10;360(6404):542. doi: 10.1038/360542a0. Nature. 1992. PMID: 1461278 No abstract available.

Abstract

The per locus of Drosophila has been implicated in the control of behavioural rhythms. In fruitfly embryos and larvae per is expressed in salivary glands. Per mutations have striking effects on intercellular communication in salivary glands: gap junction channels are modulated so that their conductance varies inversely with the period of behavioural rhythms in the mutants. A similar effect on junctional communication in the nervous system may explain how per influences behavioural rhythms.

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