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. 2013 Jun;8(3):221-9.
doi: 10.1159/000351692.

13th st. Gallen international breast cancer conference 2013: primary therapy of early breast cancer evidence, controversies, consensus - opinion of a german team of experts (zurich 2013)

Michael Untch  1 , Bernd Gerber  2 , Nadia Harbeck  3 , Christian Jackisch  4 , Norbert Marschner  5 , Volker Möbus  6 , Gunter von Minckwitz  7 , Sibylle Loibl  8 , Matthias W Beckmann  9 , Jens-Uwe Blohmer  10 , Serban-Dan Costa  11 , Thomas Decker  12 , Ingo Diel  13 , Thomas Dimpfl  14 , Wolfgang Eiermann  15 , Tanja Fehm  16 , Klaus Friese  17 , Fritz Jänicke  18 , Wolfgang Janni  19 , Walter Jonat  20 , Marion Kiechle  21 , Uwe Köhler  22 , Hans-Joachim Lück  23 , Nicolai Maass  24 , Kurt Possinger  25 , Achim Rody  26 , Anton Scharl  27 , Andreas Schneeweiss  28 , Christoph Thomssen  29 , Diethelm Wallwiener  30 , Anja Welt  31
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13th st. Gallen international breast cancer conference 2013: primary therapy of early breast cancer evidence, controversies, consensus - opinion of a german team of experts (zurich 2013)

Michael Untch et al. Breast Care (Basel). 2013 Jun.

Abstract
in English, German

The International Consensus Conference on the treatment of primary breast cancer takes place every two years in St. Gallen, Switzerland. The panel in St. Gallen is composed of international experts from different countries. From a German perspective, it seems reasonable to interpret the voting results in the light of AGO-recommendations and S3-guidelines for everyday practice in Germany. Consequently, a team of eight breast cancer experts, of whom two are members of the international St. Gallen panel, commented on the voting results of the St. Gallen Consensus Conference (2013). The main topics at this year's St. Gallen conference were surgical issues of the breast and axilla, radio-therapeutic and systemic treatment options, and the clinical relevance of tumour biology. The clinical utility of multigene assays for supporting individual treatment decisions was also intensively discussed.

Alle zwei Jahre findet in St. Gallen (Schweiz) die internationale Konsensuskonferenz zur Behandlung des primären Mammakarzinoms statt. Da sich das internationale Panel in St. Gallen aus Experten unterschiedlicher Länder zusammensetzt, spiegelt der Konsensus ein internationales Meinungsbild wider. Vor diesem Hintergrund erscheint es aus deutscher Sicht sinnvoll, die Abstimmungsergebnisse für den Therapiealltag in Deutschland zu konkretisieren. Eine deutsche Arbeitsgruppe mit acht Brustkrebsexperten, von denen zwei Mitglieder des internationalen St. Gallen-Panels sind, hat daher die Abstimmungsergebnisse der St. Gallen-Konsensuskonferenz (2013) für den Klinikalltag in Deutschland kommentiert. Inhaltliche Schwerpunkte der diesjährigen St. Gallen-Konferenz waren operative Fragestellungen der Brust und der Axilla, strahlentherapeutische und systemische Therapieoptionen sowie die klinische Relevanz der Tumorbiologie. Intensiv diskutiert wurde der klinische Einsatz von Multigen-Assays, inkl. ihrer Bedeutung für die individuelle Therapieentscheidung.

Keywords: Adjuvant therapy; Early breast cancer; Multigene signatures; St. Gallen Consensus; Targeted therapy.

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