"Spontaneous" complete remissions in chronic lymphocytic leukemia: report of three cases and review of the literature
- PMID: 2441780
"Spontaneous" complete remissions in chronic lymphocytic leukemia: report of three cases and review of the literature
Abstract
"Spontaneous" complete remissions (SCR) are a rare event in chronic lymphocytic leukemia (CLL). In this article, we report three cases of SCR observed in a series of 285 patients followed at a single institution during the last 15 years. SCR was documented by clinical and hematologic data, including bone marrow biopsy, and immune cell markers. A delay of 0.9-1.6 years between "clinical" and "clonal" remission was observed. A review of other cases of SCR in CLL is also performed.
Similar articles
-
Spontaneous remission of B-cell chronic lymphocytic leukemia associated with T lymphocytic hyperplasia in bone marrow.South Med J. 2002 Jun;95(6):647-9. South Med J. 2002. PMID: 12081222
-
Remission of chronic lymphocytic leukemia after smallpox vaccination.Arch Intern Med. 1978 Jul;138(7):1137-8. Arch Intern Med. 1978. PMID: 666477
-
[Bone marrow immunophenotypes of 112 cases of lymphoid system malignant diseases].Ai Zheng. 2007 Apr;26(4):418-22. Ai Zheng. 2007. PMID: 17430665 Chinese.
-
Biology of chronic lymphocytic leukemia.Semin Hematol. 1987 Oct;24(4):209-29. Semin Hematol. 1987. PMID: 3317850 Review.
-
Chronic lymphoid leukemias: recent advances in biology and therapy.Stem Cells. 1995 Jan;13(1):1-21. doi: 10.1002/stem.5530130103. Stem Cells. 1995. PMID: 7719244 Review.
Cited by
-
Immunopeptidome Diversity in Chronic Lymphocytic Leukemia Identifies Patients with Favorable Disease Outcome.Cancers (Basel). 2022 Sep 25;14(19):4659. doi: 10.3390/cancers14194659. Cancers (Basel). 2022. PMID: 36230581 Free PMC article.
-
Hodgkin's disease developing after spontaneous remission of chronic lymphocytic leukemia.Ann Hematol. 1995 Nov;71(5):247-52. doi: 10.1007/BF01744374. Ann Hematol. 1995. PMID: 7492627 Review.
-
Complete Immunophenotypic Reversal of Chronic Lymphocytic Leukaemia With High Dose Parenteral Methylcobalamin: A Case Report and Brief Review of Cobalamin in Cancer.Cancer Rep (Hoboken). 2025 May;8(5):e70106. doi: 10.1002/cnr2.70106. Cancer Rep (Hoboken). 2025. PMID: 40347057 Free PMC article. Review.
-
Development of a dendritic cell-based vaccine for chronic lymphocytic leukemia.Cancer Immunol Immunother. 2008 Nov;57(11):1705-10. doi: 10.1007/s00262-008-0561-y. Epub 2008 Jul 29. Cancer Immunol Immunother. 2008. PMID: 18663443 Free PMC article. Review.
-
Identification of protamine 1 as a novel cancer-testis antigen in early chronic lymphocytic leukaemia.Br J Haematol. 2009 Mar;144(5):660-6. doi: 10.1111/j.1365-2141.2008.07502.x. Epub 2008 Nov 22. Br J Haematol. 2009. PMID: 19036087 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources
Medical