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Case Reports
. 1987;12(2):471-83.

"Spontaneous" complete remissions in chronic lymphocytic leukemia: report of three cases and review of the literature

J M Ribera, N Viñolas, A Urbano-Ispizua, T Gallart, E Montserrat, C Rozman
  • PMID: 2441780
Case Reports

"Spontaneous" complete remissions in chronic lymphocytic leukemia: report of three cases and review of the literature

J M Ribera et al. Blood Cells. 1987.

Abstract

"Spontaneous" complete remissions (SCR) are a rare event in chronic lymphocytic leukemia (CLL). In this article, we report three cases of SCR observed in a series of 285 patients followed at a single institution during the last 15 years. SCR was documented by clinical and hematologic data, including bone marrow biopsy, and immune cell markers. A delay of 0.9-1.6 years between "clinical" and "clonal" remission was observed. A review of other cases of SCR in CLL is also performed.

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