Response to Belgard et al

E Skafidas¹, R Testa², D Zantomio³, G Chana⁴, I P Everall⁵, C Pantelis⁶

Affiliations

¹ 1] Centre for Neural Engineering, The University of Melbourne, Parkville, VIC, Australia [2] Department of Psychiatry, Melbourne Neuropsychiatry Centre, The University of Melbourne and Melbourne Health, National Neuroscience Facility (NNF), Parkville, VIC, Australia [3] National ICT Australia, The University of Melbourne, Parkville, VIC, Australia [4] Florey Institute of Neurosciences and Mental Health, Melbourne Brain Centre, Parkville, VIC, Australia.
² 1] Centre for Neural Engineering, The University of Melbourne, Parkville, VIC, Australia [2] Department of Psychiatry, Melbourne Neuropsychiatry Centre, The University of Melbourne and Melbourne Health, National Neuroscience Facility (NNF), Parkville, VIC, Australia [3] Department of Psychology, Monash University, Clayton, VIC, Australia.
³ Department of Haematology, Austin Health, Heidelberg, VIC, Australia.
⁴ 1] Centre for Neural Engineering, The University of Melbourne, Parkville, VIC, Australia [2] National ICT Australia, The University of Melbourne, Parkville, VIC, Australia [3] Department of Psychiatry, The University of Melbourne, Parkville, VIC, Australia.
⁵ 1] Florey Institute of Neurosciences and Mental Health, Melbourne Brain Centre, Parkville, VIC, Australia [2] Department of Psychiatry, The University of Melbourne, Parkville, VIC, Australia [3] NorthWestern Mental Health, Melbourne Health, Parkville, VIC, Australia.
⁶ 1] Department of Psychiatry, Melbourne Neuropsychiatry Centre, The University of Melbourne and Melbourne Health, National Neuroscience Facility (NNF), Parkville, VIC, Australia [2] Florey Institute of Neurosciences and Mental Health, Melbourne Brain Centre, Parkville, VIC, Australia [3] Department of Psychiatry, The University of Melbourne, Parkville, VIC, Australia [4] NorthWestern Mental Health, Melbourne Health, Parkville, VIC, Australia.

PMID: 24419040
PMCID: PMC3965835
DOI: 10.1038/mp.2013.186

Free PMC article

Comment

Response to Belgard et al

E Skafidas et al. Mol Psychiatry. 2014 Apr.

Free PMC article

. 2014 Apr;19(4):407-9.

doi: 10.1038/mp.2013.186. Epub 2014 Jan 14.

Authors

E Skafidas¹, R Testa², D Zantomio³, G Chana⁴, I P Everall⁵, C Pantelis⁶

Affiliations

¹ 1] Centre for Neural Engineering, The University of Melbourne, Parkville, VIC, Australia [2] Department of Psychiatry, Melbourne Neuropsychiatry Centre, The University of Melbourne and Melbourne Health, National Neuroscience Facility (NNF), Parkville, VIC, Australia [3] National ICT Australia, The University of Melbourne, Parkville, VIC, Australia [4] Florey Institute of Neurosciences and Mental Health, Melbourne Brain Centre, Parkville, VIC, Australia.
² 1] Centre for Neural Engineering, The University of Melbourne, Parkville, VIC, Australia [2] Department of Psychiatry, Melbourne Neuropsychiatry Centre, The University of Melbourne and Melbourne Health, National Neuroscience Facility (NNF), Parkville, VIC, Australia [3] Department of Psychology, Monash University, Clayton, VIC, Australia.
³ Department of Haematology, Austin Health, Heidelberg, VIC, Australia.
⁴ 1] Centre for Neural Engineering, The University of Melbourne, Parkville, VIC, Australia [2] National ICT Australia, The University of Melbourne, Parkville, VIC, Australia [3] Department of Psychiatry, The University of Melbourne, Parkville, VIC, Australia.
⁵ 1] Florey Institute of Neurosciences and Mental Health, Melbourne Brain Centre, Parkville, VIC, Australia [2] Department of Psychiatry, The University of Melbourne, Parkville, VIC, Australia [3] NorthWestern Mental Health, Melbourne Health, Parkville, VIC, Australia.
⁶ 1] Department of Psychiatry, Melbourne Neuropsychiatry Centre, The University of Melbourne and Melbourne Health, National Neuroscience Facility (NNF), Parkville, VIC, Australia [2] Florey Institute of Neurosciences and Mental Health, Melbourne Brain Centre, Parkville, VIC, Australia [3] Department of Psychiatry, The University of Melbourne, Parkville, VIC, Australia [4] NorthWestern Mental Health, Melbourne Health, Parkville, VIC, Australia.

PMID: 24419040
PMCID: PMC3965835
DOI: 10.1038/mp.2013.186

Erratum in

Mol Psychiatry. 2014 Jun;19(6):743-4

No abstract available

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Figures

**Figure 1**
Percentage of individuals classified as ASD as a function of the number of single-nucleotide polymorphisms (SNPs) ordered in decreasing absolute magnitude. Significant variance was observed at smaller number of SNPs (not plotted). Note the gradient differential between SFARI cases versus FIN and GBR between SNPs 80 and 150. ASD, autism spectrum disorder; SNPs, single-nucleotide polymorphisms; SFARI-CASES, Simons Foundation Autism Research Initiative ASD probands; population samples from the 1000 genome cohort: GBR, Great British; FIN, Finnish.

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Comment on

Predicting the diagnosis of autism spectrum disorder using gene pathway analysis.
Skafidas E, Testa R, Zantomio D, Chana G, Everall IP, Pantelis C. Skafidas E, et al. Mol Psychiatry. 2014 Apr;19(4):504-10. doi: 10.1038/mp.2012.126. Epub 2012 Sep 11. Mol Psychiatry. 2014. PMID: 22965006 Free PMC article.
Population structure confounds autism genetic classifier.
Belgard TG, Jankovic I, Lowe JK, Geschwind DH. Belgard TG, et al. Mol Psychiatry. 2014 Apr;19(4):405-7. doi: 10.1038/mp.2013.34. Epub 2013 Apr 2. Mol Psychiatry. 2014. PMID: 23546168 Free PMC article. No abstract available.

References

1. Belgard TG, Jankovic I, Lowe JK, Geschwind DH.Mol Psychiatrydoi:10.1038/mp.2013.34(e-pub ahead of print). - DOI - PMC - PubMed
1. Skafidas E, Testa R, Zantomio D, Chana G, Everall IP, Pantelis C.Mol Psychiatrydoi:10.1038/mp.2012.126(e-pub ahead of print). - DOI - PMC - PubMed
1. Abecasis GR, Auton A, Brooks LD, DePristo MA, Durbin RM, Handsaker RE, et al. Nature. 2012. pp. 56–65. - PMC - PubMed
1. Centers for Disease Control and Prevention Surveillance Summaries. 2012. pp. 1–19. - PubMed

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Response to Belgard et al

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Response to Belgard et al

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