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Multicenter Study
. 2014 Jan 1;65(1):82-6.
doi: 10.1097/QAI.0b013e3182a685dc.

Incidence of hepatocellular carcinoma in HIV-infected patients with cirrhosis: a prospective study

Collaborators, Affiliations
Multicenter Study

Incidence of hepatocellular carcinoma in HIV-infected patients with cirrhosis: a prospective study

María Luisa Montes Ramírez et al. J Acquir Immune Defic Syndr. .

Abstract

: This study assesses the incidence of hepatocellular carcinoma (HCC) in a prospective cohort of HIV-infected patients, the majority receiving antiretroviral therapy, with liver cirrhosis from different etiologies, enrolled between 2004 and 2005 with median follow-up of 5 years. We followed 371 patients, 25.6% with decompensated cirrhosis at baseline. The incidence rate of HCC was 6.72 per 1000 person-years [95% confidence interval (CI): 2.6 to 10.9]. There was a trend toward a higher cumulative probability of developing HCC at 6 years of follow-up (considering death and liver transplant as competing risks) in patients with decompensated versus compensated cirrhosis at baseline (6% vs. 2%, P < 0.06).

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