doi: 10.1016/0014-4827(87)90178-9.
The blocked pinocytic activity of mitotic cells is restored in mitotic-interphase hybrids
- PMID: 2442020
- DOI: 10.1016/0014-4827(87)90178-9
Item in Clipboard
The blocked pinocytic activity of mitotic cells is restored in mitotic-interphase hybrids
Exp Cell Res.
1987 Aug.
Abstract
During mitosis there is an abrupt inhibition of a wide range of membrane functions, including fluid-phase and adsorptive pinocytosis. We have used cell hybrids formed between mitotic and interphase cells to approach the mechanism of this inhibition. We report that fluid pinocytosis is reactivated in the mitotic partner of hybrids formed between mitotic and interphase Chinese hamster ovary (CHO) cells. It thus appears that the interphase cell provides some necessary element(s) for membrane activity during mitosis. This dominance of interphase membrane properties stands in contrast with earlier evidence that mitotic nuclear properties dominate in similar mitotic-interphase hybrids.
Similar articles
-
Surface functions during Mitosis I: phagocytosis, pinocytosis and mobility of surface-bound Con A.Cell. 1978 Oct;15(2):327-41. doi: 10.1016/0092-8674(78)90002-8. Cell. 1978. PMID: 719746
-
Microtubule dynamics at the G2/M transition: abrupt breakdown of cytoplasmic microtubules at nuclear envelope breakdown and implications for spindle morphogenesis.J Cell Biol. 1996 Oct;135(1):201-14. doi: 10.1083/jcb.135.1.201. J Cell Biol. 1996. PMID: 8858174 Free PMC article.
-
Nuclear reassembly excludes large macromolecules.Science. 1987 Oct 23;238(4826):548-50. doi: 10.1126/science.2443981. Science. 1987. PMID: 2443981
-
Cell cycle mutants of mammalian cells in culture. Present interest and limits to the study of thermodependent mutants.Biol Cell. 1984;51(3):295-306. doi: 10.1111/j.1768-322x.1984.tb00308.x. Biol Cell. 1984. PMID: 6240999 Review.
-
Fluorescent labeling of endocytic compartments.Methods Cell Biol. 1989;29:137-51. doi: 10.1016/s0091-679x(08)60192-2. Methods Cell Biol. 1989. PMID: 2464119 Review. No abstract available.