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. 2013 Feb;18(2):86-90.
doi: 10.1093/pch/18.2.86.

Bronchopulmonary dysplasia - trends over three decades

Zofia Zysman-Colman  1 , Genevieve M Tremblay  2 , Suhair Bandeali  3 , Jennifer S Landry  4
Affiliations

Bronchopulmonary dysplasia - trends over three decades

Zofia Zysman-Colman et al. Paediatr Child Health. 2013 Feb.

Abstract
in English, French

Objectives: To describe the characteristics of bronchopulmonary dysplasia (BPD) and respiratory distress syndrome subjects, along with the trends in severity and mortality associated with BPD over the past three decades.

Methods: Retrospective study of BPD and respiratory distress syndrome subjects born between 1980 and 2008, and admitted to Montreal Children's Hospital (Montreal, Quebec). Data were abstracted from hospital records.

Results: Gestational age and birth weight were correlated with the occurrence of BPD with each additional week of gestation and 100 g in birth weight being associated with an OR of developing BPD of 0.77 and 0.89, respectively. BPD severity was associated with male sex, Apgar score and the occurrence of neonatal pneumonia. Significant trends were observed for lower mortality despite lower gestational age and birth weight, greater maternal age and multiple gestations.

Conclusion: Mortality from BPD has improved over the past three decades despite significant trends toward more pronounced prematurity and lower birth weights.

Objectif: Décrire les caractéristiques des sujets atteints de la dysplasie bronchopulmonaire (DBP) et du syndrome de détresse respiratoire, de même que les tendances quant à la gravité de la DBP et à la mortalité s’y rapportant depuis 30 ans.

Méthodologie: Les chercheurs ont mené une étude rétrospective des sujets atteints de la DBP et du syndrome de détresse respiratoire nés entre 1980 et 2008 et hospitalisés à L’Hôpital de Montréal pour enfants, au Québec. Ils ont tiré les données des dossiers hospitaliers.

Résultats: Les chercheurs ont corrélé l’âge gestationnel et le poids de naissance avec l’occurrence de DBP, chaque nouvelle semaine de grossesse et nouvelle tranche de 100 g de poids de naissance s’associant à un RRR de DBP de 0,77 et de 0,89, respectivement. La gravité de la DBP s’associait au sexe masculin, à l’indice d’Apgar et à l’occurrence d’une pneumonie néonatale. Les chercheurs ont observé des tendances importantes de diminution de la mortalité malgré un âge gestationnel et un poids de naissance moins élevés, l’âge plus avancé des mères et des gestations multiples.

Conclusion: La mortalité liée à la DBP a diminué depuis 30 ans, malgré des tendances importantes vers une prématurité plus prononcée et un plus petit poids à la naissance.

Keywords: Bronchopulmonary dysplasia; Infant respiratory distress syndrome; Preterm birth.

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Figures

Figure 1)
Figure 1)
Trends in multiple gestation, maternal age, gestational age and birth weight in bronchopulmonary dysplasia (BDP) and respiratory distress syndrome (RDS) subjects over the past three decades
Figure 2)
Figure 2)
Trends in bronchopulmonary dysplasia (BPD) severity and mortality among preterm infants with respiratory distress syndrome (RDS) over the past three decades
See this image and copyright information in PMC

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