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. 2014 Jan 24;77(1):173-7.
doi: 10.1021/np400761g. Epub 2014 Jan 14.

Tetramic acid analogues produced by coculture of Saccharopolyspora erythraea with Fusarium pallidoroseum

James Whitt  1 , Suzanne M Shipley, David J Newman, Karina M Zuck
Affiliations

Tetramic acid analogues produced by coculture of Saccharopolyspora erythraea with Fusarium pallidoroseum

James Whitt et al. J Nat Prod. .

Abstract

Coculture of the fungus Fusarium pallidoroseum with the bacterium Saccharopolyspora erythraea was found to produce three new decalin-type tetramic acid analogues related to equisetin. The structures were determined by spectroscopic methods. The absolute configurations were established by circular dichroism spectroscopy and comparing the data with those of equisetin.

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Figures

Figure 1
Figure 1
Chromatogram in positive ion mode (m/z 350–450 uma) of the extracts of Fusarium pallidoroseum (top), Saccharopolyspora erythraea (bottom), and coculture (middle) showing the new peaks observed only in the coculture (1–3 are new metabolites, 4 is ophiosetin, and 5 is equisetin).
See this image and copyright information in PMC

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