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. 2014 Jan 14:348:f7003.
doi: 10.1136/bmj.f7003.

WHO guidelines on fluid resuscitation in children: missing the FEAST data

Sarah Kiguli  1 , Samuel O Akech, George Mtove, Robert O Opoka, Charles Engoru, Peter Olupot-Olupot, Richard Nyeko, Jennifer Evans, Jane Crawley, Natalie Prevatt, Hugh Reyburn, Michael Levin, Elizabeth C George, Annabelle South, Abdel G Babiker, Diana M Gibb, Kathryn Maitland
Affiliations

WHO guidelines on fluid resuscitation in children: missing the FEAST data

Sarah Kiguli et al. BMJ. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Competing interests: We have read and understood the BMJ Group policy on declaration of interests and declare SK, SOA, GM, ROO, CE, POO, RN, HR, and KM were principal or co-principal investigators on the FEAST trial, and AB, DMG, and JC were on the trial’s steering committee.

Watch the video “FEAST: anatomy of a trial” at www.youtube.com/watch?v=bS68W8AQjds&feature=c4-overview&list=UUxUK9Zn4Es5SxMbAYeTSO2g.

Provenance and peer review: Not commissioned; externally peer reviewed.

Figures

Figure
Figure
RPBERTO SCHMIDT/AFP/GETTY IMAGES
See this image and copyright information in PMC

Comment in

  • Concerns about intravenous fluids given to critically ill children.
    Southall D. Southall D. BMJ. 2014 Feb 19;348:g1617. doi: 10.1136/bmj.g1617. BMJ. 2014. PMID: 24554465 No abstract available.
  • Authors' reply to Southall.
    Kiguli S, Akech SO, Mtove G, Opoka RO, Engoru C, Olupot-Olupot P, Nyeko R, Evans J, Crawley J, Prevatt N, Reyburn H, Levin M, George EC, South A, Babiker AG, Gibb DM, Maitland K. Kiguli S, et al. BMJ. 2014 Feb 19;348:g1619. doi: 10.1136/bmj.g1619. BMJ. 2014. PMID: 24554466 No abstract available.

References

    1. World Health Organization. Guidelines for the management of common childhood illnesses. 2nd ed. WHO; 2013. Pocket book of hospital care for children. - PubMed
    1. Maitland K, Kiguli S, Opoka RO, Engoru C, Olupot-Olupot P, Akech SO, et al. Mortality after fluid bolus in African children with severe infection. N Engl J Med. 2011;364:2483–95. - PubMed
    1. Ford N, Hargreaves S, Shanks L. Mortality after fluid bolus in children with shock due to sepsis or severe infection: a systematic review and meta-analysis. PLoS One. 2012;7:e43953. - PMC - PubMed
    1. Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intens Care Med. 2008;34:17–60. - PMC - PubMed
    1. Brierley J, Carcillo JA, Choong K, Cornell T, Decaen A, Deymann A, et al. Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine. Crit Care Med. 2009;37:666–88. - PMC - PubMed