Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Oct;61(10):3319-21.
doi: 10.1128/JVI.61.10.3319-3321.1987.

Action of 3-methylquercetin on poliovirus RNA replication

J L Castrillo, L Carrasco

Action of 3-methylquercetin on poliovirus RNA replication

J L Castrillo et al. J Virol. 1987 Oct.

Abstract

3-Methylquercetin is a natural flavone that powerfully blocks poliovirus replication. This compound inhibits selectively poliovirus RNA synthesis both in infected cells and in cell-free systems. Poliovirus double-stranded RNA (replicative forms) is still made in the presence of this inhibitor, whereas the synthesis of single-stranded RNA and the formation of replicative intermediates are drastically blocked.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Virology. 1986 Jul 15;152(1):219-27 - PubMed
    1. J Virol. 1986 Oct;60(1):43-53 - PubMed
    1. Proc Natl Acad Sci U S A. 1963 Jun;49:843-9 - PubMed
    1. J Mol Biol. 1968 Mar 14;32(2):359-68 - PubMed
    1. Virology. 1970 Sep;42(1):112-22 - PubMed

Publication types

LinkOut - more resources