IL-17: a key player in the P. acnes inflammatory cascade?
- PMID: 24424453
- DOI: 10.1038/jid.2013.400
IL-17: a key player in the P. acnes inflammatory cascade?
Abstract
Recent advances in our understanding of inflammatory skin diseases now afford an opportunity to delve deeper into microbial/host interactions in acne. Agak et al. report that Propionibacterium acnes induces IL-17 expression in peripheral blood mononuclear cells and present new evidence that IL-17+ cells are found in the perifollicular infiltrate of comedones. Additional studies are needed to assess the clinical relevance of IL-17 in acne.
Comment on
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Propionibacterium acnes Induces an IL-17 Response in Acne Vulgaris that Is Regulated by Vitamin A and Vitamin D.J Invest Dermatol. 2014 Feb;134(2):366-373. doi: 10.1038/jid.2013.334. Epub 2013 Aug 7. J Invest Dermatol. 2014. PMID: 23924903 Free PMC article.
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