Bacillus thuringiensis growth, sporulation and δ-endotoxin production in oxygen limited and non-limited cultures
- PMID: 24425483
- DOI: 10.1007/BF01201884
Bacillus thuringiensis growth, sporulation and δ-endotoxin production in oxygen limited and non-limited cultures
Abstract
The production of crystals and spores ofBacillus thuringiensis var.israelensis was studied under different aeration conditions. The results with 4 l batch cultures showed that for O2 non-limited, cultures cell yield, toxin production and spore count were constant for all oxygen transfer rates (OTR). Under O2 limitation, °-endotoxin concentrations and spore counts were lower than those obtained in non-limited cultures. In addition, δ-endotoxin yields diminished under O2 limitation, suggesting that the toxin synthesis mechanism could have been affected.