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Meta-Analysis
. 2014 Jan 15;2014(1):CD008963.
doi: 10.1002/14651858.CD008963.pub2.

Self-management education programmes for osteoarthritis

Affiliations
Meta-Analysis

Self-management education programmes for osteoarthritis

Féline P B Kroon et al. Cochrane Database Syst Rev. .

Abstract

Background: Self-management education programmes are complex interventions specifically targeted at patient education and behaviour modification. They are designed to encourage people with chronic disease to take an active self-management role to supplement medical care and improve outcomes.

Objectives: To assess the effectiveness of self-management education programmes for people with osteoarthritis.

Search methods: The Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, PyscINFO, SCOPUS and the World Health Organization (WHO) International Clinical Trial Registry Platform were searched, without language restriction, on 17 January 2013. We checked references of reviews and included trials to identify additional studies.

Selection criteria: Randomised controlled trials of self-management education programmes in people with osteoarthritis were included. Studies with participants receiving passive recipients of care and studies comparing one type of programme versus another were excluded.

Data collection and analysis: In addition to standard methods we extracted components of the self-management interventions using the eight domains of the Health Education Impact Questionnaire (heiQ), and contextual and participant characteristics using PROGRESS-Plus and the Health Literacy Questionnaire (HLQ). Outcomes included self-management of osteoarthritis, participant's positive and active engagement in life, pain, global symptom score, self-reported function, quality of life and withdrawals (including dropouts and those lost to follow-up). We assessed the quality of the body of evidence for these outcomes using the GRADE approach.

Main results: We included twenty-nine studies (6,753 participants) that compared self-management education programmes to attention control (five studies), usual care (17 studies), information alone (four studies) or another intervention (seven studies). Although heterogeneous, most interventions included elements of skill and technique acquisition (94%), health-directed activity (85%) and self-monitoring and insight (79%); social integration and support were addressed in only 12%. Most studies did not provide enough information to assess all PROGRESS-Plus items. Eight studies included predominantly Caucasian, educated female participants, and only four provided any information on participants' health literacy. All studies were at high risk of performance and detection bias for self-reported outcomes; 20 studies were at high risk of selection bias, 16 were at high risk of attrition bias, two were at high risk of reporting bias and 12 were at risk of other biases. We deemed attention control as the most appropriate and thus the main comparator.Compared with attention control, self-management programmes may not result in significant benefits at 12 months. Low-quality evidence from one study (344 people) indicates that self-management skills were similar in active and control groups: 5.8 points on a 10-point self-efficacy scale in the control group, and the mean difference (MD) between groups was 0.4 points (95% confidence interval (CI) -0.39 to 1.19). Low-quality evidence from four studies (575 people) indicates that self-management programmes may lead to a small but clinically unimportant reduction in pain: the standardised mean difference (SMD) between groups was -0.26 (95% CI -0.44 to -0.09); pain was 6 points on a 0 to 10 visual analogue scale (VAS) in the control group, treatment resulted in a mean reduction of 0.8 points (95% CI -0.14 to -0.3) on a 10-point scale, with number needed to treat for an additional beneficial outcome (NNTB) of 8 (95% CI 5 to 23). Low-quality evidence from one study (251 people) indicates that the mean global osteoarthritis score was 4.2 on a 0 to 10-point symptom scale (lower better) in the control group, and treatment reduced symptoms by a mean of 0.14 points (95% CI -0.54 to 0.26). This result does not exclude the possibility of a clinically important benefit in some people (0.5 point reduction included in 95% CI). Low-quality evidence from three studies (574 people) showed no signficant difference in function between groups (SMD -0.19, 95% CI -0.5 to 0.11); mean function was 1.29 points on a 0 to 3-point scale in the control group, and treatment resulted in a mean improvement of 0.04 points with self-management (95% CI -0.10 to 0.02). Low-quality evidence from one study (165 people) showed no between-group difference in quality of life (MD -0.01, 95% CI -0.03 to 0.01) from a control group mean of 0.57 units on 0 to 1 well-being scale. Moderate-quality evidence from five studies (937 people) shows similar withdrawal rates between self-management (13%) and control groups (12%): RR 1.11 (95% CI 0.78 to 1.57). Positive and active engagement in life was not measured.Compared with usual care, moderate-quality evidence from 11 studies (up to 1,706 participants) indicates that self-management programmes probably provide small benefits up to 21 months, in terms of self-management skills, pain, osteoarthritis symptoms and function, although these are of doubtful clinical importance, and no improvement in positive and active engagement in life or quality of life. Withdrawal rates were similar. Low to moderate quality evidence indicates no important differences in self-management , pain, symptoms, function, quality of life or withdrawal rates between self-management programmes and information alone or other interventions (exercise, physiotherapy, social support or acupuncture).

Authors' conclusions: Low to moderate quality evidence indicates that self-management education programmes result in no or small benefits in people with osteoarthritis but are unlikely to cause harm.Compared with attention control, these programmes probably do not improve self-management skills, pain, osteoarthritis symptoms, function or quality of life, and have unknown effects on positive and active engagement in life. Compared with usual care, they may slightly improve self-management skills, pain, function and symptoms, although these benefits are of unlikely clinical importance.Further studies investigating the effects of self-management education programmes, as delivered in the trials in this review, are unlikely to change our conclusions substantially, as confounding from biases across studies would have likely favoured self-management. However, trials assessing other models of self-management education programme delivery may be warranted. These should adequately describe the intervention they deliver and consider the expanded PROGRESS-Plus framework and health literacy, to explore issues of health equity for recipients.

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Conflict of interest statement

RB and RHO were investigators for one of the included trials but had no part in deciding on inclusion, assessment of risk of bias, data extraction or interpretation of the results (Ackerman 2012).

Figures

1
1
Flowchart.
2
2
Summary of the risk of bias across all included studies.
3
3
Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
4
4
Funnel plot of comparison: 3 SMP versus Usual care/No treatment/Wait list, outcome: 3.1 Self‐management of OA.
5
5
Funnel plot of comparison: 3 SMP versus Usual care/No treatment/Wait list, outcome: 3.3 Dropouts.
6
6
Funnel plot of comparison: 3 SMP versus Usual care/No treatment/Wait list, outcome: 3.4 Pain.
1.1
1.1. Analysis
Comparison 1 SMP versus attention control, Outcome 1 Self‐management of OA.
1.2
1.2. Analysis
Comparison 1 SMP versus attention control, Outcome 2 Pain.
1.3
1.3. Analysis
Comparison 1 SMP versus attention control, Outcome 3 Global OA scores.
1.4
1.4. Analysis
Comparison 1 SMP versus attention control, Outcome 4 Function—self‐reported.
1.5
1.5. Analysis
Comparison 1 SMP versus attention control, Outcome 5 Quality of life.
1.6
1.6. Analysis
Comparison 1 SMP versus attention control, Outcome 6 Withdrawals.
1.7
1.7. Analysis
Comparison 1 SMP versus attention control, Outcome 7 Emotional distress.
2.1
2.1. Analysis
Comparison 2 SMP versus usual care/no treatment/wait list, Outcome 1 Self‐management of OA.
2.2
2.2. Analysis
Comparison 2 SMP versus usual care/no treatment/wait list, Outcome 2 Engagement in life.
2.3
2.3. Analysis
Comparison 2 SMP versus usual care/no treatment/wait list, Outcome 3 Pain.
2.4
2.4. Analysis
Comparison 2 SMP versus usual care/no treatment/wait list, Outcome 4 Global OA scores.
2.5
2.5. Analysis
Comparison 2 SMP versus usual care/no treatment/wait list, Outcome 5 Function—self‐reported.
2.6
2.6. Analysis
Comparison 2 SMP versus usual care/no treatment/wait list, Outcome 6 Function—performance.
2.7
2.7. Analysis
Comparison 2 SMP versus usual care/no treatment/wait list, Outcome 7 Quality of life.
2.8
2.8. Analysis
Comparison 2 SMP versus usual care/no treatment/wait list, Outcome 8 Withdrawals.
2.9
2.9. Analysis
Comparison 2 SMP versus usual care/no treatment/wait list, Outcome 9 Emotional distress.
2.10
2.10. Analysis
Comparison 2 SMP versus usual care/no treatment/wait list, Outcome 10 Health‐directed activity.
2.11
2.11. Analysis
Comparison 2 SMP versus usual care/no treatment/wait list, Outcome 11 Skill and technique acquisition.
2.12
2.12. Analysis
Comparison 2 SMP versus usual care/no treatment/wait list, Outcome 12 Constructive attitudes and approaches.
2.13
2.13. Analysis
Comparison 2 SMP versus usual care/no treatment/wait list, Outcome 13 Social integration and support.
2.14
2.14. Analysis
Comparison 2 SMP versus usual care/no treatment/wait list, Outcome 14 Health service navigation.
3.1
3.1. Analysis
Comparison 3 SMP versus information only, Outcome 1 Self‐management of OA.
3.2
3.2. Analysis
Comparison 3 SMP versus information only, Outcome 2 Engagement in life.
3.3
3.3. Analysis
Comparison 3 SMP versus information only, Outcome 3 Pain.
3.4
3.4. Analysis
Comparison 3 SMP versus information only, Outcome 4 Global OA scores.
3.5
3.5. Analysis
Comparison 3 SMP versus information only, Outcome 5 Function—self‐reported.
3.6
3.6. Analysis
Comparison 3 SMP versus information only, Outcome 6 Function—performance.
3.7
3.7. Analysis
Comparison 3 SMP versus information only, Outcome 7 Quality of life.
3.8
3.8. Analysis
Comparison 3 SMP versus information only, Outcome 8 Withdrawals.
3.9
3.9. Analysis
Comparison 3 SMP versus information only, Outcome 9 Emotional distress.
3.10
3.10. Analysis
Comparison 3 SMP versus information only, Outcome 10 Health‐directed activity.
3.11
3.11. Analysis
Comparison 3 SMP versus information only, Outcome 11 Social integration and support.
3.12
3.12. Analysis
Comparison 3 SMP versus information only, Outcome 12 Health service navigation.
3.13
3.13. Analysis
Comparison 3 SMP versus information only, Outcome 13 Skill and technique acquisition.
3.14
3.14. Analysis
Comparison 3 SMP versus information only, Outcome 14 Constructive attitudes and approaches.
4.1
4.1. Analysis
Comparison 4 SMP versus non‐SMP intervention, Outcome 1 Self‐management of OA.
4.2
4.2. Analysis
Comparison 4 SMP versus non‐SMP intervention, Outcome 2 Pain.
4.3
4.3. Analysis
Comparison 4 SMP versus non‐SMP intervention, Outcome 3 Global OA scores.
4.4
4.4. Analysis
Comparison 4 SMP versus non‐SMP intervention, Outcome 4 Function—self‐reported.
4.5
4.5. Analysis
Comparison 4 SMP versus non‐SMP intervention, Outcome 5 Function—performance.
4.6
4.6. Analysis
Comparison 4 SMP versus non‐SMP intervention, Outcome 6 Quality of life.
4.7
4.7. Analysis
Comparison 4 SMP versus non‐SMP intervention, Outcome 7 Withdrawals.
4.8
4.8. Analysis
Comparison 4 SMP versus non‐SMP intervention, Outcome 8 Emotional distress.
4.9
4.9. Analysis
Comparison 4 SMP versus non‐SMP intervention, Outcome 9 Constructive attitudes and approaches.
5.1
5.1. Analysis
Comparison 5 SMP versus acupuncture, Outcome 1 Global OA scores.
5.2
5.2. Analysis
Comparison 5 SMP versus acupuncture, Outcome 2 Pain.
5.3
5.3. Analysis
Comparison 5 SMP versus acupuncture, Outcome 3 Function self‐reported.
5.4
5.4. Analysis
Comparison 5 SMP versus acupuncture, Outcome 4 Function performance.
5.5
5.5. Analysis
Comparison 5 SMP versus acupuncture, Outcome 5 Withdrawals.
6.1
6.1. Analysis
Comparison 6 Subgroup analysis, Outcome 1 Self‐management in OA.
6.2
6.2. Analysis
Comparison 6 Subgroup analysis, Outcome 2 Function self‐reported.
6.3
6.3. Analysis
Comparison 6 Subgroup analysis, Outcome 3 Pain.
6.4
6.4. Analysis
Comparison 6 Subgroup analysis, Outcome 4 Withdrawals.

Update of

  • doi: 10.1002/14651858.CD008963

References

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Laforest 2008a {published data only}
    1. Laforest S, Nour K, Parisien M, Poirier MC, Gignac M, Lankoande H. "I'm taking charge of my arthritis": designing a targeted self‐management program for frail seniors. Physical and Occupational Therapy in Geriatrics 2008;26:45‐66.
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Martire 2003a {published data only}
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Martire 2008 {published data only}
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References to studies awaiting assessment

Allen 2011 {published data only}
    1. Allen KD, Bosworth HB, Coffman C, Lindquist JH, Sperber NR, Weinberger M, et al. Effects of a telephone based osteoarthritis self‐management program on communication with health care providers. Arthritis and Rheumatism 2011;63(Suppl 10):1582.
Coleman 2012 {published data only}
    1. Coleman S, Briffa NK, Carroll G, Inderjeeth C, Cook N, McQuade J. A randomised controlled trial of a self‐management education program for osteoarthritis of the knee delivered by health care professionals. Arthritis Research and Therapy 2012;14(1):R21. - PMC - PubMed
Hurley 2012 {published data only}
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Schlenk 2011 {published data only}
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    1. Huebner JL, Landerman LR, Somers TJ, Kraus VB, Guilak F, Blumenthal JA, et al. Inflammatory biomarkers of OA, IL‐6 and leptin are modifiable in overweight/obese OA patients with a protocol that combines training in pain coping skills and weight management. Osteoarthritis and Cartilage 2012;20:S38.
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Stukstette 2011 {published data only}
    1. Stukstette MJ, Dekker J, Broeder AA, Laan WN, Bijlsma JWJ, Ende CHM. A multidisciplinary and multidimensional program for hand osteoarthritis is not effective: results of a randomized controlled study. Arthritis and Rheumatism 2011;63(Suppl 10):1570.
Von Korff 2012 {published data only}
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Wu 2011 {published data only}
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References to ongoing studies

Allen 2012 {published data only}
    1. Allen KD, Bosworth HB, Brock DS, Chapman JG, Chatterjee R, Coffman CJ, et al. Patient and provider interventions for managing osteoarthritis in primary care: protocols for two randomized controlled trials. BMC Musculoskeletal Disorders 2012;13:60. - PMC - PubMed
Bennell 2012 {published data only}
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