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. 1992 Jul;8(4):406-10.
doi: 10.1007/BF01198755.

Phenylalanine ammonia lyase fromSporidiobolus pararoseus andRhodosporidium toruloides: Application for phenylalanine and tyrosine deamination

S Kawasaki Watanabe  1 , G Hernandez-Velazco, F Iturbe-Chiñas, A Lopez-Munguia
Affiliations

Phenylalanine ammonia lyase fromSporidiobolus pararoseus andRhodosporidium toruloides: Application for phenylalanine and tyrosine deamination

S Kawasaki Watanabe et al. World J Microbiol Biotechnol. 1992 Jul.

Abstract

Simultaneous depletion of phenylalanine and tyrosine by phenylalanine ammonia lyase is described in a mutual competitive inhibition model. The enzymes obtained fromSporidiobolus pararoseus andRhodosporidium toruloides were charaterized in terms of stability, optimal reaction parameters and kinetic behaviour. Both enzymes followed Michaelis-Menten kinetics with respect to the two amino acids. However, the enzyme fromRhodosporidium toruloides was inhibited by high tyrosine concentrations.

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