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Review
. 2013 Jun;50(3):415-28.
doi: 10.1007/s13197-012-0775-z. Epub 2012 Jul 19.

Nutrigenomics research: a review

V S Neeha  1 , Priyamvadah Kinth  1
Affiliations
Review

Nutrigenomics research: a review

V S Neeha et al. J Food Sci Technol. 2013 Jun.

Abstract

The excitement about nutrigenomics comes from a growing awareness of the potential for modifications of food or diet to support health and reduce the risk of diet-related diseases. It is an emerging field that tends to unfold the role of nutrition on gene expression which brings together the science of bioinformatics, nutrition, molecular biology, genomics, epidemiology, and molecular medicine. The present review focuses on nutrigenomics research and to find out India's status with respect to other countries. It covers the general overview of nutrigenomics, its associated diseases, and the role of SNP in gene alteration, diet supplementation and public awareness. It is understood that with the increasing changes in the food habits and life styles, people are becoming more prone to diet related disorders. Therefore there is an urgent need to boost more research in this field to help people in understanding the relationship between diet and health, and to ensure that everyone benefits from the genomic revolution.

Keywords: Diabetes; Diet-gene interaction; Food supplement; Nutrigenomics; Nutrition; Obesity.

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Figures

Fig. 1
Fig. 1
Estimated number of Diabetic subjects in India. Source: Mohan et al. ,
Fig. 2
Fig. 2
Estimated mortality from coronary heart disease. Source: Trehan
Fig. 3
Fig. 3
a Projected prevalence of overweight males in India aged 30 years or more, 2005 and 2015. Source: WHO Reportb Projected prevalence of overweight females in India aged 30 years or more, 2005 and 2015. Source: WHO Report
Fig. 4
Fig. 4
Country-wise contribution to nutrigenomics research. Source: Scopus Database
Fig. 5
Fig. 5
Subject-wise contribution to nutrigenomics research. Source: Scopus Database
Fig. 6
Fig. 6
Nutrigenomics approach in disease prevention
Fig. 7
Fig. 7
Single Nucleotide Polymorphism, its associated gene alteration and diseases. Source: Modified from Mitra et al. (2005)
Fig. 8
Fig. 8
Food dietary guidelines
See this image and copyright information in PMC

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