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. 2013 Dec 15;7(1):456-9.
eCollection 2014.

Ovarian sclerosing stromal tumor in a young woman with ectopic pregnancy: clinical, pathological, and immunohistochemical studies

Yan-Fang Liang  1 , Jin-Cheng Zeng  2 , Jian-Bo Ruan  1 , Dong-Ping Kang  1 , Ling-Mei Wang  1 , Can Chen  1 , Jun-Fa Xu  2
Affiliations

Ovarian sclerosing stromal tumor in a young woman with ectopic pregnancy: clinical, pathological, and immunohistochemical studies

Yan-Fang Liang et al. Int J Clin Exp Pathol. .

Abstract

In this article, we described an ovarian sclerosing stromal tumor (SST) in a young woman with ectopic pregnancy. It is important to distinguish SST from fibroma, thecoma, and lipoid cell tumors clinically and histologically. Several unique histologic features including pseudolobulation, sclerosis and prominent vascularity are clearly reflected at histopathological findings. The SST cells were immunopositive for CD34, Desmin and SMA, and negative for factor VIII-related antigen, CD31, S-100, ER and PR. The patient's postoperative recovery was smooth and she was discharged after 21 days.

Keywords: Ovarian stromal tumor; ectopic pregnancy; immunohistochemistry.

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Figures

Figure 1
Figure 1
The ovarian mass and fallopian tube were stained with hematoxylin and eosin. A: Cellular pseudolobular pattern separated by edematous fibrous bands and prominent or dilated thin-walled blood vessels in sclerosing stromal tumors (40×). B: Two distinct cell populations of spindle-shaped fibroblasts admixed with polygonal vacuolated cells in sclerosing stromal tumors (200×). C: Trophoblast cells, Villi, and blood clot were visible in fallopian tube.
Figure 2
Figure 2
The cells were immunopositive for CD34, desmin, SMA and Vim in sclerosing stromal tumors (200×).
See this image and copyright information in PMC

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