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. 2014 Jan;6(1):36-40.
doi: 10.1177/1941738113502296.

Muscle changes in aging: understanding sarcopenia

Patrick N Siparsky  1 , Donald T Kirkendall  2 , William E Garrett Jr  1
Affiliations

Muscle changes in aging: understanding sarcopenia

Patrick N Siparsky et al. Sports Health. 2014 Jan.

Abstract

Muscle physiology in the aging athlete is complex. Sarcopenia, the age-related decrease in lean muscle mass, can alter activity level and affect quality of life. This review addresses the microscopic and macroscopic changes in muscle with age, recognizes contributing factors including nutrition and changes in hormone levels, and identifies potential pharmacologic agents in clinical trial that may aid in the battle of this complex, costly, and disabling problem.

Level of evidence: Level 5.

Keywords: SARMs; aging athlete; muscle aging; sarcopenia.

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Conflict of interest statement

The following authors declared potential conflicts of interest: Donald. T. Kirkendall, PhD, received payment for lectures from US Youth Soccer and royalties from Human Kinetics Publishers; William E. Garrett, Jr, MD, PhD, received grants or has grants pending from GSK.

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