doi: 10.1021/ol4035929.
Epub 2014 Jan 15.
Ruthenium-catalyzed dimerization of propiolates: a simple route to α-pyrones
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- PMID: 24428195
- DOI: 10.1021/ol4035929
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Ruthenium-catalyzed dimerization of propiolates: a simple route to α-pyrones
Org Lett.
.
Abstract
A ruthenium-catalyzed regioselective intermolecular multistep homo- and heterodimerization of substituted propiolates providing α-pyrone-5-carboxylates and α-pyrone-6-carboxylates is described. The synthetic utilities of α-pyrone derivatives are shown. The proposed mechanism is strongly supported by experimental evidence.
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