[Use of misoprostol in gynaecology]

Abstract

Objectives: To assess the interest of misoprostol in gynaecology and particularly for cervical priming.

Method: Research in PubMed in English and French about misoprostol and its use in gynaecology.

Results: We summarized the results of 3 meta-analyses, randomized controlled trials and literature review. Results show that misoprostol did not scientifically prove a benefit for cervical priming before hysteroscopy or before intra-uterine device (IUD). Results are the same with post-menopausal or nulliparous women. It did not lead either to lower the complications but increase adverse effects.

Conclusion: It is not indicated to use misoprostol for cervical priming in gynaecology.

Keywords: Cervical priming; DIU; Dilatation cervicale; Hysteroscopy; Hystéroscopie; IUD; Misoprostol.