Ho(a)xing autophagy to regulate development
- PMID: 24434134
- DOI: 10.1016/j.devcel.2013.12.018
Ho(a)xing autophagy to regulate development
Abstract
In this issue of Developmental Cell, Banreti et al. (2014) demonstrate that canonical autophagy is inhibited in the Drosophila fat body by Hox transcriptional factors. This regulation involves repression of the Atg genes. Programmed developmental autophagy is thus under Hox control and may influence cell fate determination.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
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Hox proteins mediate developmental and environmental control of autophagy.Dev Cell. 2014 Jan 13;28(1):56-69. doi: 10.1016/j.devcel.2013.11.024. Epub 2014 Jan 2. Dev Cell. 2014. PMID: 24389064
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