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Comment
. 2014 Jan 13;28(1):3-4.
doi: 10.1016/j.devcel.2013.12.018.

Ho(a)xing autophagy to regulate development

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Ho(a)xing autophagy to regulate development

Silvia Campello et al. Dev Cell. .
Free article

Abstract

In this issue of Developmental Cell, Banreti et al. (2014) demonstrate that canonical autophagy is inhibited in the Drosophila fat body by Hox transcriptional factors. This regulation involves repression of the Atg genes. Programmed developmental autophagy is thus under Hox control and may influence cell fate determination.

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