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Review
. 2013 Mar;22(1):1-8.
doi: 10.1055/s-0032-1331840.

An overview of optimal endovascular strategy in treating the femoropopliteal artery: mechanical, biological, and procedural factors

Affiliations
Review

An overview of optimal endovascular strategy in treating the femoropopliteal artery: mechanical, biological, and procedural factors

Nicolas W Shammas. Int J Angiol. 2013 Mar.

Abstract

Treatment of the femoropopliteal (FP) artery remains a challenge to the endovascular specialist. Long-term patency is low with a high rate of target lesion revascularization. The true patency rate varies considerably between studies partly because there is a lack of uniform performance criteria and reporting standards in peripheral arterial interventions. Literature review supports three principles that emerge as important components of an optimal strategy in treating the FP artery: (1) improving vessel compliance and subsequently less dissections and bailout stenting, (2) reducing smooth muscle cell proliferation, and (3) protecting outflow vessels from distal embolization. In this overview, we examine current data that support the validity of this strategy.

Keywords: atherectomy; distal embolization; drug-coated balloon; femoropopliteal artery; in-stent restenosis; restenosis; tibial runoff.

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Conflict of interest statement

Note The author has no commercial, proprietary, or financial interest in any products described in this article. Dr Shammas received related research and educational grants to the Midwest Cardiovascular Research Foundation from eV3 (Covidien), Spectranetics, and CSI. Supported by the Nicolas and Gail Shammas Research Fund at MCRF. Full disclosure at www.mcrfmd.com.

Figures

Fig. 1
Fig. 1
The triad of an optimal peripheral vascular revascularization strategy addresses vessel mechanics and biological responses and optimizes procedural variables to ensure distal vessel protection and operator and patient safety.

References

    1. Shammas N W. Epidemiology, classification, and modifiable risk factors of peripheral arterial disease. Vasc Health Risk Manag. 2007;3(2):229–234. - PMC - PubMed
    1. Anderson P L, Gelijns A, Moskowitz A. et al.Understanding trends in inpatient surgical volume: vascular interventions, 1980–2000. J Vasc Surg. 2004;39(6):1200–1208. - PubMed
    1. Kandarpa K, Becker G J, Hunink M G. et al.Transcatheter interventions for the treatment of peripheral atherosclerotic lesions: part I. J Vasc Interv Radiol. 2001;12(6):683–695. - PubMed
    1. Laird J R. Limitations of percutaneous transluminal angioplasty and stenting for the treatment of disease of the superficial femoral and popliteal arteries. J Endovasc Ther. 2006;13 02:II30–II40. - PubMed
    1. Shammas N W. Optimal strategy in lower extremity peripheral percutaneous interventions: an interventionalist's perspective. Vasc Dis Manage. 2009;6:36–40.