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Review
. 2013 Sep;26(3):153-9.
doi: 10.1055/s-0033-1351130.

Venous thromboembolism prophylaxis

Jonathan Laryea  1 , Bradley Champagne  2
Affiliations
Review

Venous thromboembolism prophylaxis

Jonathan Laryea et al. Clin Colon Rectal Surg. 2013 Sep.

Abstract

Venous thromboembolism (VTE) can occur after major general surgery. Pulmonary embolism is recognized as the most common identifiable cause of death in hospitalized patients in the United States. The risk of deep venous thrombosis (DVT) and pulmonary embolism (PE) is higher in colorectal surgical procedures compared with general surgical procedures. The incidence of venous thromboembolism in this population is estimated to be 0.2 to 0.3%. Prevention of VTE is considered a patient-safety measure in most mandated quality initiatives. The measures for prevention of VTE include mechanical methods (graduated compression stockings and intermittent pneumatic compression devices) and pharmacologic agents. A combination of mechanical and pharmacologic methods produces the best results. Patients undergoing surgery should be stratified according to their risk of VTE based on patient risk factors, disease-related risk factors, and procedure-related risk factors. The type of prophylaxis should be commensurate with the risk of VTE based on the composite risk profile.

Keywords: deep venous thrombosis; mechanical agents; pharmacologic agents; prevention; pulmonary embolism; risk stratification; venous thromboembolism.

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References

    1. McLeod R S, Geerts W H, Sniderman K W. et al. Canadian Colorectal Surgery DVT Prophylaxis Trial investigators . Subcutaneous heparin versus low-molecular-weight heparin as thromboprophylaxis in patients undergoing colorectal surgery: results of the canadian colorectal DVT prophylaxis trial: a randomized, double-blind trial. Ann Surg. 2001;233(3):438–444. - PMC - PubMed
    1. Horlander K T, Mannino D M, Leeper K V. Pulmonary embolism mortality in the United States, 1979-1998: an analysis using multiple-cause mortality data. Arch Intern Med. 2003;163(14):1711–1717. - PubMed
    1. Lindblad B, Eriksson A, Bergqvist D. Autopsy-verified pulmonary embolism in a surgical department: analysis of the period from 1951 to 1988. Br J Surg. 1991;78(7):849–852. - PubMed
    1. Stein P D, Henry J W. Prevalence of acute pulmonary embolism among patients in a general hospital and at autopsy. Chest. 1995;108(4):978–981. - PubMed
    1. White R H, Zhou H, Romano P S. Incidence of symptomatic venous thromboembolism after different elective or urgent surgical procedures. Thromb Haemost. 2003;90(3):446–455. - PubMed