Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Jul:388:437-47.
doi: 10.1113/jphysiol.1987.sp016623.

Selectivity and patch measurements of A-current channels in Helix aspersa neurones

P S Taylor  1
Affiliations

Selectivity and patch measurements of A-current channels in Helix aspersa neurones

P S Taylor. J Physiol. 1987 Jul.

Abstract

1. The ionic selectivity of A-current K+ channels has been measured in single Helix aspersa neurones by recording the reversal potential shift in test solutions containing various monovalent cations. 2. The A-current channel is permeable to Tl+, K+, Rb+, NH4+ and Cs+. The channels may also be sparingly permeable to Na+ and Li+. Organic cations have an apparent small permeability as judged from their reversal potentials, but this may be an artifact of K+ accumulation. 3. A large patch electrode (3 microns tip) isolated a region that appeared to contain only A-current channels. This may indicate that A-current channels are found in the membrane as rafts of at least 3 microns in diameter. 4. The single-channel conductance calculated from single-channel current steps was 14 pS.

PubMed Disclaimer

References

    1. J Gen Physiol. 1966 Mar;49(4):629-40 - PubMed
    1. J Physiol. 1961 Mar;155:470-89 - PubMed
    1. J Gen Physiol. 1971 Jul;58(1):36-53 - PubMed
    1. Pflugers Arch. 1972;336(2):87-100 - PubMed
    1. J Gen Physiol. 1973 Jun;61(6):669-86 - PubMed

Publication types

LinkOut - more resources