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. 2014 Mar;103(3):504-9.
doi: 10.1016/j.diabres.2013.12.014. Epub 2013 Dec 27.

All-cause mortality in a population-based type 1 diabetes cohort in the U.S. Virgin Islands

Raynard E Washington  1 , Trevor J Orchard  2 , Vincent C Arena  3 , Ronald E LaPorte  2 , Aaron M Secrest  2 , Eugene S Tull  2
Affiliations

All-cause mortality in a population-based type 1 diabetes cohort in the U.S. Virgin Islands

Raynard E Washington et al. Diabetes Res Clin Pract. 2014 Mar.

Abstract

Objective: Type 1 diabetes remains a significant source of premature mortality; however, its burden has not been assessed in the U.S. Virgin Islands (USVI). As such, the objective of this study was to estimate type 1 diabetes mortality in a population-based registry sample in the USVI.

Research design and methods: We report overall and 20-year mortality in the USVI Childhood (<19 years old) Diabetes Registry Cohort diagnosed 1979-2005. Recent data for non-Hispanic blacks from the Allegheny County, PA population-based type 1 diabetes registry were used to compare mortality in the USVI to the contiguous U.S.

Results: As of December 31, 2010, the vital status of 94 of 103 total cases was confirmed (91.3%) with mean diabetes duration 16.8 ± 7.0 years. No deaths were observed in the 2000-2005 cohort. The overall mortality rates for those diagnosed 1979-1989 and 1990-1999 were 1852 and 782 per 100,000 person-years, respectively. Overall cumulative survival for USVI was 98% (95% CI: 97-99) at 10 years, 92% (95% CI: 89-95) at 15 years and 73% (95% CI: 66-80) at 20 years. The overall SMR for non-Hispanic blacks in the USVI was 5.8 (95% CI: 2.7-8.8). Overall mortality and cumulative survival for non-Hispanic blacks did not differ between the USVI and Allegheny County, PA.

Conclusions: This study, as the first type 1 diabetes mortality follow-up in the USVI, confirmed previous findings of poor disease outcomes in racial/ethnic minorities with type 1 diabetes.

Keywords: Health disparities; Mortality; Type 1 diabetes; Virgin Islands.

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Conflict of interest statement

All authors (REW, TJO, VCA, REL, AMS, EST) have no potential conflicts of interest.

Figures

Figure 1
Figure 1. Life-Table Analysis Overall in Non-Hispanic Blacks in USVI (1979-2005) vs. Allegheny County (1965-1979)
See this image and copyright information in PMC

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