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Review
. 2014 Feb;21(2):232-49.
doi: 10.1016/j.acra.2013.11.002.

The pivotal role of FDG-PET/CT in modern medicine

Søren Hess  1 , Björn A Blomberg  2 , Hongyun June Zhu  3 , Poul Flemming Høilund-Carlsen  4 , Abass Alavi  5
Affiliations
Review

The pivotal role of FDG-PET/CT in modern medicine

Søren Hess et al. Acad Radiol. 2014 Feb.

Abstract

The technology behind positron emission tomography (PET) and the most widely used tracer, 2-deoxy-2-[18F]fluoro-D-glucose (FDG), were both conceived in the 1970s, but the latest decade has witnessed a rapid emergence of FDG-PET as an effective imaging technique. This is not least due to the emergence of hybrid scanners combining PET with computed tomography (PET/CT). Molecular imaging has enormous potential for advancing biological research and patient care, and FDG-PET/CT is currently the most widely used technology in this domain. In this review, we discuss contemporary applications of FDG-PET and FDG-PET/CT as well as novel developments in quantification and potential future indications including the emerging new modality PET/magnetic resonance imaging.

Keywords: 2-deoxy-2-[18F]fluoro-D-glucose; FDG; PET/CT; Positron emission tomography/computed tomography; molecular imaging.

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