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Comment
. 2014 Jan 16;156(1-2):13-4.
doi: 10.1016/j.cell.2013.12.037.

The shape of things to come

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The shape of things to come

Orkun Akin et al. Cell. .
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Abstract

Surface receptors can link binding of ligands to changes in the actin-based cell cytoskeleton. Chia et al. and Chen et al. provide evidence for direct binding between the cytoplasmic tails of receptors and the WAVE complex, a regulator of the actin nucleator Arp2/3 complex, which might help to explain how environmental signals are translated into changes in morphology and motility.

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