Myelin formation and remodeling
- PMID: 24439366
- PMCID: PMC5017146
- DOI: 10.1016/j.cell.2013.12.038
Myelin formation and remodeling
Abstract
Myelin is a multilayer wrapping of insulation formed by glial cells around axons that is essential for rapid impulse transmission, but how glial cells accomplish this cellular choreography has long intrigued researchers. In this issue of Cell, Snaidero et al., provide new insights into how myelin forms and is remodeled.
Copyright © 2014 Elsevier Inc. All rights reserved.
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Myelin membrane wrapping of CNS axons by PI(3,4,5)P3-dependent polarized growth at the inner tongue.Cell. 2014 Jan 16;156(1-2):277-90. doi: 10.1016/j.cell.2013.11.044. Cell. 2014. PMID: 24439382 Free PMC article.
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