Phagocyte roulette in Salmonella killing
- PMID: 24439894
- PMCID: PMC3936476
- DOI: 10.1016/j.chom.2014.01.001
Phagocyte roulette in Salmonella killing
Abstract
Salmonella propagates in macrophages to cause life-threatening infections, but the role of neutrophils in combating Salmonella has been controversial. In this issue, Burton et al. (2014) use single cell analyses and modeling to explain the ability of Salmonella to survive in macrophages while being killed by neutrophils.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
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Disparate impact of oxidative host defenses determines the fate of Salmonella during systemic infection in mice.Cell Host Microbe. 2014 Jan 15;15(1):72-83. doi: 10.1016/j.chom.2013.12.006. Cell Host Microbe. 2014. PMID: 24439899
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