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Randomized Controlled Trial
. 2014 Jun;22(6):1207-15.
doi: 10.1007/s00167-014-2843-6. Epub 2014 Jan 21.

Microfracture technique versus osteochondral autologous transplantation mosaicplasty in patients with articular chondral lesions of the knee: a prospective randomized trial with long-term follow-up

Svend Ulstein  1 , Asbjørn Årøen, Jan Harald Røtterud, Sverre Løken, Lars Engebretsen, Stig Heir
Affiliations
Randomized Controlled Trial

Microfracture technique versus osteochondral autologous transplantation mosaicplasty in patients with articular chondral lesions of the knee: a prospective randomized trial with long-term follow-up

Svend Ulstein et al. Knee Surg Sports Traumatol Arthrosc. 2014 Jun.

Abstract

Purpose: To compare long-term functional and radiological outcome following microfracture technique (MF) versus osteochondral autologous transplantation (OAT) mosaicplasty for treating focal chondral lesions of the knee.

Methods: Twenty-five patients (mean age 32.3 years, SD 7.7) with a full-thickness (International Cartilage Repair Society grade 3 or 4) chondral lesion of the articulating surface of the femur were randomized to either MF (n = 11) or OAT mosaicplasty (n = 14). At a median follow-up of 9.8 years (range 4.9-11.4), the patients were evaluated using Lysholm score (n = 25), Knee Injury and Osteoarthritis Outcome Score (KOOS, n = 25), isokinetic quadriceps measurement and hamstring strength measurement (n = 22) and standing radiographs (n = 23).

Results: There were no significant differences in Lysholm score, KOOS, isokinetic muscle strength or radiographic osteoarthritis between MF-treated patients and OAT mosaicplasty-treated patients at follow-up. Mean Lysholm score at follow-up was 69.7 [95% confidence interval (CI), 55.1-84.4] for the MF group and 62.6 (95% CI, 52.6-72.6) for the OAT mosaicplasty group.

Conclusion: At long-term follow-up, there were no significant differences between patients treated with MF and patients treated with OAT mosaicplasty in patient-reported outcomes, muscle strength or radiological outcome.

Level of evidence: Therapeutic study, Level II.

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Figures

Fig. 1
Fig. 1
Mean Lysholm score for patients treated with MF (n = 11) and OAT mosaicplasty (n = 14) at preoperative and follow-up. *Lysholm score acquired from a normal, healthy population as a standard point of reference for the injured or postsurgical knee, as described by Briggs, K.K. et al., Am J Sports Med, 2009
Fig. 2
Fig. 2
Knee Injury and Osteoarthritis Outcome Score (KOOS) at inclusion and follow-up for the MF group and the OAT mosaicplasty group. *Reference population as described by Paradowski et al. [35] BMC Musculoskelet Disord
See this image and copyright information in PMC

References

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