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. 1987 Oct;26(5):362-4.
doi: 10.1093/rheumatology/26.5.362.

Immunohistochemical demonstration of nociceptors in the capsule and synovial folds of human zygapophyseal joints

L G Giles  1 , A R Harvey
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Immunohistochemical demonstration of nociceptors in the capsule and synovial folds of human zygapophyseal joints

L G Giles et al. Br J Rheumatol. 1987 Oct.

Abstract

Substance P, a physiologically potent neuropeptide, is considered to participate in nociceptive transmission of nerve impulses. Substance P immunofluorescent nerves are demonstrated in the inferior joint recess capsule and its synovial folds in human lumbosacral zygapophyseal joints. This may have clinical significance in spinal pain.

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