Understanding myosin functions in plants: are we there yet?

Abstract

Myosins are motor proteins that drive movements along actin filaments and have long been assumed to be responsible for cytoplasmic streaming in plant cells. This conjecture is now firmly established by genetic analysis in the reference species, Arabidopsis thaliana. This work and similar approaches in the moss, Physcomitrella patens, also established that myosin-driven movements are necessary for cell growth and polarity, organelle distribution and shape, and actin organization and dynamics. Identification of a mechanistic link between intracellular movements and cell expansion has proven more challenging, not the least because of the high level of apparent genetic redundancy among myosin family members. Recent progress in the creation of functional complementation constructs and identification of interaction partners promises a way out of this dilemma.