Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2014 Mar 25;129(12):1273-5.
doi: 10.1161/CIRCULATIONAHA.114.008298. Epub 2014 Jan 21.

Degradation of platelet-von Willebrand factor complexes by plasmin: an alternative/backup mechanism to ADAMTS13

Anil K Chauhan  1
Affiliations
Editorial

Degradation of platelet-von Willebrand factor complexes by plasmin: an alternative/backup mechanism to ADAMTS13

Anil K Chauhan. Circulation. .
No abstract available

Keywords: ADAMTS13 protein, human; Editorials; mechanical thrombolysis; plasminogen; streptokinase; von Willebrand factor.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures: None.

Comment on

References

    1. Ruggeri ZM. Role of von willebrand factor in platelet thrombus formation. Ann Med. 2000;32 (Suppl 1):2–9. - PubMed
    1. Sporn LA, Marder VJ, Wagner DD. Von willebrand factor released from weibel-palade bodies binds more avidly to extracellular matrix than that secreted constitutively. Blood. 1987;69:1531–1534. - PubMed
    1. Dong JF, Moake JL, Nolasco L, Bernardo A, Arceneaux W, Shrimpton CN, Schade AJ, McIntire LV, Fujikawa K, Lopez JA. Adamts-13 rapidly cleaves newly secreted ultralarge von willebrand factor multimers on the endothelial surface under flowing conditions. Blood. 2002;100:4033–4039. - PubMed
    1. Sadler JE. New concepts in von willebrand disease. Annu Rev Med. 2005;56:173–191. - PubMed
    1. Levy GG, Nichols WC, Lian EC, Foroud T, McClintick JN, McGee BM, Yang AY, Siemieniak DR, Stark KR, Gruppo R, Sarode R, Shurin SB, Chandrasekaran V, Stabler SP, Sabio H, Bouhassira EE, Upshaw JD, Jr, Ginsburg D, Tsai HM. Mutations in a member of the adamts gene family cause thrombotic thrombocytopenic purpura. Nature. 2001;413:488–494. - PubMed

LinkOut - more resources