Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Mar;21(2):120-2.
doi: 10.1590/S1413-78522013000200010.

Current concepts in osteoarthritis

Márcia Uchôa de Rezende  1 , Gustavo Constantino de Campos  1 , Alexandre Felício Pailo  1
Affiliations

Current concepts in osteoarthritis

Márcia Uchôa de Rezende et al. Acta Ortop Bras. 2013 Mar.

Abstract

Osteoarthritis (OA), the most common form of joint disease, affects mainly the hips, knees, hands and feet, leading to severe disability and loss of quality of life, particularly in the elderly population. Its importance grows every year with the aging of the population, with a large increase in the elderly population compared to younger patients. The progressive understanding of the pathophysiology of OA, the perception that the process is not purely mechanical and / or aging, and clarification of the inflammatory pathways involved led recently to the clinical application of various drugs and other measures. This update aims to expose the current concepts on the pathophysiology and treatment of OA.

Keywords: Arthritis; Osteoarthritis; Osteoarthritis, hip; Osteoarthritis, knee; Osteoarthritis/physiopathology.

PubMed Disclaimer

Conflict of interest statement

Todos os autores declaram não haver nenhum potencial conflito de interesses referente a este artigo.

References

    1. Lawrence RC, Felson DT, Helmick CG, Arnold LM, Choi H, Deyo RA, et al. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis and rheumatism. 2008;58(1):26–35. - PMC - PubMed
    1. Dillon CF, Rasch EK, Gu Q, Hirsch R. Prevalence of knee osteoarthritis in the United States: arthritis data from the Third National Health and Nutrition Examination Survey 1991-94. J Rheumatol. 2006;33(11):2271–2279. - PubMed
    1. Projeção da população do Brasil por sexo e idade - 1980-2050 [database on the Internet] IBGE; 2008. http://www.ibge.gov.br/home/estatistica/populacao/projecao_da_populacao/...
    1. Le TK, Montejano LB, Cao Z, Zhao Y, Ang D. Health care costs in US patients with and without a diagnosis of osteoarthritis. J Pain Res. 2012;5:23–30. - PMC - PubMed
    1. Rezende MU, Gobbi RG. Tratamento medicamentoso da osteoartrose do joelho. Rev Bras Ortop. 2009;44(1):14–19. - PMC - PubMed

LinkOut - more resources