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. 2013:2013:147163.
doi: 10.1155/2013/147163. Epub 2013 Dec 10.

Validating efficacy of shea nut oil extract in knee osteoarthritis patients

San-Pei Chen  1 , Sui-Foon Lo  2 , Yu-Chia Wang  3 , Tzu-Yi Chou  3 , Kang-Ming Chang  4 , Li-Wei Chou  2
Affiliations

Validating efficacy of shea nut oil extract in knee osteoarthritis patients

San-Pei Chen et al. Evid Based Complement Alternat Med. 2013.

Abstract

Objectives. To examine and investigate the efficacy of shea nut oil extract (SheaFlex75) in relation to knee osteoarthritis (OA). Methods. Thirty-three patients (age 63.6 ± 5.8 years) with knee OA were recruited. Real-time ultrasound imaging and surface electromyography were used to objectively assess the morphological changes and the activity of vastus medialis oblique (VMO) muscles during a 16-week intervention of SheaFlex75. The intraclass correlation coefficient (ICC) was calculated to examine the reliability of the interscans. A paired-sample t-test was used to compare the findings in different stages. The Spearman's rank correlation coefficient was used to examine the relationship between the relevant variables of OA and percentage of thickness change of VMO at different contraction levels. Results. The baseline findings showed strong correlation, suggesting that the reliability of interscans at pretest was high. The ability to contract the muscles of the knee to a 30% contraction level showed significant change between the baseline and after 16-week testing, both in terms of morphological changes and muscle activity. Pain scale reported a significant decrease at the 16th week. Conclusion. The results suggest that SheaFlex75 can relieve the symptoms of knee OA and can result in improvement of muscle control of the knee.

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Figures

Figure 1
Figure 1
The examiner used the linear transducer to capture the image of the vastus medial (VM) at each muscle status (a) and the scanned image (b).
Figure 2
Figure 2
The scanned images of the vastus medial (VM) at three different muscle statuses. The overlay depicts the shape of VM and the distance between opposite points measured as the thickness of the VM.
Figure 3
Figure 3
Examples of electrode positions for VM and VL placement. The ultrasound and s-EMG data is synchronously collected. The experimental protocol is listed, right.
Figure 4
Figure 4
Symptom Change of VAS during the three trials (∗ indicates significant difference in comparison with the baseline).
See this image and copyright information in PMC

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