Review
doi: 10.1017/s0317167100038075.
Chorea
Affiliations
- PMID: 2445458
- DOI: 10.1017/s0317167100038075
Item in Clipboard
Review
Chorea
Can J Neurol Sci.
1987 Aug.
Abstract
A variety of neurotransmitters have been implicated in the pathophysiology of chorea as exemplified by Huntington's chorea. These include dopamine, serotonin, acetylcholine, GABA and a variety of neuropeptides including substance P and somatostatin. Despite biochemical data that suggests that alterations in other neurotransmitters may be of greater significance, pharmacologic data still supports a major role of dopamine in the actual clinical manifestation of chorea.
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