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. 2014 Jan-Feb;8(1-2):E44-7.
doi: 10.5489/cuaj.1491.

Ganglioneuroma with leiomyomatosis of the urinary bladder: A rare tumour causing frequent micturition and dysuria

Wang Qi  1 , Min Jie  1 , Zhang Tao  1 , Xie Dongdong  1 , Wang Yi  1 , Ding Demao  1 , Chen Lei  1 , Zou Ci  1 , Ma Jiaxing  1 , Zhang Zhiqiang  1 , Wang Daming  1 , Yu Dexin  1
Affiliations

Ganglioneuroma with leiomyomatosis of the urinary bladder: A rare tumour causing frequent micturition and dysuria

Wang Qi et al. Can Urol Assoc J. 2014 Jan-Feb.

Abstract

We present the case of a 34-year-old female, complaining of frequent micturition and progressive dysuria. By cystoscopy and computerized tomography, we found that she had multiple sub-mucosal protuberant lesions in the entire bladder. After surgical excision, she has thus far showed no further signs of the disease. The postoperative histopathologic examination revealed a ganglioneuroma and leiomyomatosis. Urinary bladder paraganglioma is an unusual tumour; when it is combined with leiomyomatosis, it is extremely rare. We describe the main clinical presentation, diagnostic procedures, and pathologic features. We also review the English literature.

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Figures

Fig. 1.
Fig. 1.
The postoperative anatomical specimens.
Fig. 2.
Fig. 2.
Histological slides (hematoxylin phloxine saffron stain) at 10× magnification from surgical pathology, demonstrating that the bladder smooth muscle cells had proliferated.
Fig. 3.
Fig. 3.
Histological slides (hematoxylin phloxine saffron stain) at 20× magnification from surgical pathology, demonstrating that the cell beam had formed multiple nodules.
Fig. 4.
Fig. 4.
Histological slides (hematoxylin phloxine saffron stain) at 40× magnification from surgical pathology revealing a ganglioneuroma with combined leiomyomatosis.
See this image and copyright information in PMC

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