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. 2014 Jan 15;9(1):e85257.
doi: 10.1371/journal.pone.0085257. eCollection 2014.

Ultrasonic elastography features of phyllodes tumors of the breast: a clinical research

Lu-Jing Li  1 , Hong Zeng  2 , Bing Ou  1 , Bao-Ming Luo  1 , Xiao-Yun Xiao  1 , Wen-Jing Zhong  1 , Xin-Bao Zhao  1 , Zi-Zhuo Zhao  1 , Hai-Yun Yang  1 , Hui Zhi  1
Affiliations

Ultrasonic elastography features of phyllodes tumors of the breast: a clinical research

Lu-Jing Li et al. PLoS One. .

Abstract

The purpose of this study was to analyze the ultrasonic elastography features of phyllodes tumors of the breast comparing with fibroadenomas. A retrospective database was queried for the patients diagnosed as phyllodes tumors and fibroadenomas at Sun Yat-sen Memorial Hospital from January 2008 to August 2012. Three hundred and fifty lesions from 323 consecutive patients were included in the study. All the cases were examined by conventional ultrasonography and ultrasound elastography. Ultrasound elastography was used to calculate strain ratio of the lesions with bilateral breast tissue at the same depth as reference. There were 36 phyllodes tumors (27 benign, 8 borderline, 1 malignant) and 314 fibroadenomas (158 the pericanalicular type, 103 the intracanalicular type, 53 other special types). The strain ratio for phyllodes tumors (3.19 ± 2.33) was significantly higher than for fibroadenomas (1.69 ± 0.88) (p<0.05). The Spearman(.)s correlation coefficient between strain ratio of ultrasound elastography and pathological groups was significant, with a value of 0.17 (p<0.05). Ultrasound elastography could provide additional information to differentiate phyllodes tumors from fibroadenoma in breast.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Image of a benign phyllodes tumor in a 42-year-old woman.
Left: On elasticity image, the strain ratio was 3.10. Middle: Conventional B-mode image is shown. Right: Pathologic section of lesion is shown.
Figure 2
Figure 2. Image of a borderline phyllodes tumor in a 55-year-old woman.
Left: On elasticity image, the strain ratio was 5.30. Middle: Conventional B-mode image is shown. Right: Pathologic section of lesion is shown.
Figure 3
Figure 3. Image of a fibroadenoma in type II in a 29-year-old woman.
Left: On elasticity image, the entire lesion was evenly shaded in green (score 1). Middle: Conventional B-mode image is shown. Right: Pathologic section of lesion is shown.
Figure 4
Figure 4. Image of a fibroadenoma in type I in a 25-year-old woman.
Left: On elasticity image, most part of the lesion was green, but with some blue ultrasound elastography areas (score 2). Middle: Conventional B-mode image is shown. Right: Pathologic section of lesion is shown.
See this image and copyright information in PMC

References

    1. Rowell MD, Perry RR, Hsiu JG, Barranco SC (1993) Phyllodes tumors. AmJ Surg 376–379. - PubMed
    1. Kaufman CS, Bachman B, lttrup PJ, White M, Carolin KA, et al. (2002) Office based ultrasound-guided cryoablation of the breast fibroadenomas. Am J Surg 394–400. - PubMed
    1. Buchberger W, Strasser K, Heim K, Muller E, Schrocksnade H (1991) Phylloides tumor: findings on mammography, sonography, and aspiration cytology in 10 cases. AJR Am J Roentgenol 715–719. - PubMed
    1. Cole-Beuglet C, Soriano RZ, Kurtz AB, Meyer JE, Kopans DB, et al. (1983) Ultrasound, X-ray mammography, and histopathology of cystosarcoma phylloides. Radiology 481–486. - PubMed
    1. Feder JM, de Paredes ES, Hogge JP, Wilken JJ (1999) Unusual breast lesions: radiologic-pathologic correlation. Radiographics 11–26. - PubMed

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