Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2013 Dec 1;5(5):e291-4.
doi: 10.4317/jced.51178.

Endodontic management of open apex using MTA and platelet - rich fibrin membrane barrier: A newer matrix concept

Ambica Khetarpal  1 , Sarika Chaudhry  2 , Sangeeta Talwar  3 , Mahesh Verma  4
Affiliations
Case Reports

Endodontic management of open apex using MTA and platelet - rich fibrin membrane barrier: A newer matrix concept

Ambica Khetarpal et al. J Clin Exp Dent. .

Abstract

Objectives: Endodontic management of open apex using MTA and platelet - rich fibrin membrane as an apical matrix barrier.

Study design: An immature tooth with pulpal necrosis and periapical pathology imposes a great difficulty to the endodontist. Endodontic treatment options for such teeth consist of conventional apexification procedure with and without apical barriers. This article demonstrates the use of an apical matrix barrier in form of a platelet rich fibrin membrane for stabilization of MTA in root end apexification procedure. PRF is an autologous fibrin matrix containing a large quantity of platelet and leukocyte cytokines, which enhance healing by release of growth factors. These case reports present apexification and successful healing with combined use of MTA and PRF membrane as an apical barrier Results: PRF membrane can serve as an efficient apical matrix for condensation of MTA. Combination of PRF membrane and MTA is an effective method for management of difficult cases of open apex. PRF is a strong fibrin membrane enriched with platelet and growth factors that accelerate periapical healing. Key words:Apexification, apical barrier, platelet rich fibrin (PRF), mineral trioxide (MTA).

PubMed Disclaimer

Conflict of interest statement

Conflict of interest statement: The authors have declared that no conflict of interest exist.

Figures

Figure 1
Figure 1
a) Diagnostic radiograph; b) MTA plug; c) Post obturation radiograph; d) Healing evident after 3 months.
Figure 2
Figure 2
a) Centrifuge; b) 3 layers: top is platelet poor plasma, middle is PRF, and bottom layer contains red blood cells (RBC’s); c) PRF membrane in gauze; d) Carrying PRF membrane in the canal to form matrix.
Figure 3
Figure 3
a) Preoperative radiograph; b) MTA plug; c) Post obturation radiograph; d) Healing eident after 3 months.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Giuliani V, Baccetti T, Pace R. The use of MTA in teeth with necrotic pulps and open apices. Dent Traumatol. 2002;18:217–21. - PubMed
    1. Coviello J, Brilliant JD. A preliminary clinical study on the use of tricalciumphosphate as an apical barrier. J Endod. 1979;5:6–13. - PubMed
    1. Nevins A, Finkelstein F, Laporta R, Borden BG. Induction of hard tissue into pulpless open-apex teeth using collagen-calcium phosphate gel. J Endod. 1978;4:76–81. - PubMed
    1. Dimashkieh MR. A method of using silver amalgam in routine endodontics, and its use in open apices. Br Dent J. 1975;138:298–300. - PubMed
    1. Eleazer PD, McDonald TW, Sinai IH, Fantasia JE, Michelich RJ, Yagiela JA. Proplast as an apical barrier in root canal therapy. J Endod. 1984;10:487–90. - PubMed

Publication types

LinkOut - more resources