Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Observational Study
. 2014 May;103(5):488-93.
doi: 10.1111/apa.12567. Epub 2014 Mar 20.

Cerebral oxygenation after birth - a comparison of INVOS(®) and FORE-SIGHT™ near-infrared spectroscopy oximeters

Trine W Hessel  1 , Simon Hyttel-Sorensen, Gorm Greisen
Affiliations
Free PMC article
Observational Study

Cerebral oxygenation after birth - a comparison of INVOS(®) and FORE-SIGHT™ near-infrared spectroscopy oximeters

Trine W Hessel et al. Acta Paediatr. 2014 May.
Free PMC article

Abstract

Aim: To compare absolute values of regional cerebral tissue oxygenation (cStO2 ) during haemodynamic transition after birth and repeatability during steady state for two commercial near-infrared spectroscopy (NIRS) devices.

Methods: In a prospective observational study, the INVOS 5100C and FORE-SIGHT were compared on 12 term newborns delivered by elective caesarean section. During the 10 min following umbilical cord clamping, cStO2 was measured simultaneously with the neonatal sensors from each device. Repeated measurements were taken the following day.

Results: Three and 8 min after clamping, the mean cStO2 value increased from 53.4% (CI 36.8-69.9%) to 86.0% (CI 80.2-91.7%) for INVOS and from 61.6% (CI 55.4-67.8%) to 82.2% (CI 77.7-86.7%) for FORE-SIGHT. The Bland-Altman plot revealed decreasing difference (INVOS minus FORE-SIGHT) (D) in absolute values (A) with increasing cStO2 (D = 0.5A - 38.19 p = <0.001). The mean steady-state value on day two was 78.4% (CI 74.6-82.2%) and 86.2% (CI 85.0-87.4%) for INVOS and FORE-SIGHT, respectively. The within-subject standard deviation during steady-state repeated measurements was 4.8% ± 0.86 for INVOS and 2.8% ± 0.5 for FORE-SIGHT.

Conclusion: The INVOS and FORE-SIGHT cStO2 estimates showed oxygenation-level-dependent difference during birth transition. The better repeatability of FORE-SIGHT could be due to the lower response to change in saturation.

Keywords: Cerebral oxygenation; Near-infrared spectroscopy; Newborn; Transition.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Arterial saturation using pulse oximeter (mean, 95% CI).
Figure 2
Figure 2
a. Cerebral oxygenation for INVOS (mean, 95% CI). b. Cerebral oxygenation for FORE‐SIGHT (mean, 95% CI).
Figure 3
Figure 3
Bland–Altman plot (mean, limits of agreement).
See this image and copyright information in PMC

References

    1. Dullenkopf A. Measurement of cerebral oxygenation state in anaesthetized children using the INVOS 5100 cerebral oximeter. Peadiatr Anaest 2003; 3: 1–8 - PubMed
    1. Greisen G. Is near‐infrared spectroscopy living up to its promises? Semin Fetal Neonatal Med 2006; 11: 498–502 - PubMed
    1. Yoshitani K, Kawaguchi M, Tatsumi K, Kitaguchi K, Furuya H. A comparison of the INVOS 4100 and the NIRO 300 near‐infrared spectrophotometers. Anesth Analg 2002; 94: 586–90 - PubMed
    1. Komiyama T, Quaresima V, Shigematsu H, Ferrari M. Comparison of two spatially resolved near‐infrared photometers in the detection of tissue oxygen saturation: poor reliability at very low oxygen saturation. Clin Sci 2001; 101: 715–8 - PubMed
    1. Noori S, Wlodaver A, Gottipati V, McCoy M, Schultz D, Escobedo M. Transitional changes in cardiac and cerebral hemodynamics in term neonates at birth. J Pediatr 2012; 160: 943–8 - PubMed

Publication types

LinkOut - more resources